Evidence map›Paper›PMID 36836846›Full record

ReviewLife (Basel, Switzerland)2023

The Evolution of the Sentinel Node Biopsy in Melanoma.

Alexandra Allard-Coutu, Victoria Dobson, Erika Schmitz, Hely Shah, Carolyn Nessim

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Sentinel Lymph Node Biopsy in Melanoma: Overview and Updates.International journal of molecular sciences · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alexandra Allard-CoutuDepartment of General Surgery, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Victoria DobsonIndependent Researcher, Kitchener, ON N6A 3K7, Canada.
Erika SchmitzDepartment of General Surgery, University of Ottawa, Ottawa, ON K1N 6N5, Canada.ORCID 0000-0003-1094-565X
Hely ShahDepartment of Medical Oncology, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Carolyn NessimDepartment of General Surgery, University of Ottawa, Ottawa, ON K1N 6N5, Canada.ORCID 0000-0002-0419-3511
University of Ottawa · CAEmmanuel Bible College · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing repertoire of approved immune-checkpoint inhibitors and targeted therapy has revolutionized the adjuvant treatment of melanoma. While the treatment of primary cutaneous melanoma remains wide local excision (WLE), the management of regional lymph nodes continues to evolve in light of practice-changing clinical trials and dramatically improved adjuvant therapy. With large multicenter studies reporting no benefit in overall survival for completion lymph node dissection (CLND) after a positive sentinel node biopsy (SLNB), controversy remains regarding patient selection and clinical decision-making. This review explores the evolution of the SLNB in cutaneous melanoma in the context of a rapidly changing adjuvant treatment landscape, summarizing the key clinical trials which shaped current practice guidelines.

Indexed as

completion lymph node dissection (CLND)immunotherapymelanomasentinel node biopsy (SLNB)targeted therapy

Identifiers

PMID36836846
PMCPMC9966203
OpenAlexW4319971887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.