Evidence map›Paper›PMID 36836690›Full record

ReviewLife (Basel, Switzerland)2023

Impact of Immune Cells in the Tumor Microenvironment of Prostate Cancer Metastasis.

Justin K Messex, Geou-Yarh Liou

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Human Group IIA Secreted Phospholipase AInternational journal of molecular sciences · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. A Metastasis-competent CAF Subpopulation Defined byRecent patents on anti-cancer drug discovery · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. International journal of molecular sciences · 2025
    Article
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  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Justin K MessexCenter for Cancer Research and Therapeutic Development, Clark Atlanta University, Atlanta, GA 30314, USA.
Geou-Yarh LiouCenter for Cancer Research and Therapeutic Development, Clark Atlanta University, Atlanta, GA 30314, USA.ORCID 0000-0003-2728-3752
Center for Cancer Research · US

Funding

To Investigate Molecular Mechanisms of Aging-Related Growth of the Prostate - Implications in Prostate Tumorigenesis and Cancer TreatmentU54MD007590 · NIMHD · CLARK ATLANTA UNIVERSITY · PI Cimona Vaughn Hinton Dirickson · 2019 to 2026
$17.1M
Dissecting mechanisms of tumor initiation via immunomodulationSC1GM140907 · NIGMS · CLARK ATLANTA UNIVERSITY · PI LIOU, GEOU-YARH · 2021 to 2024
$1.3M
NIGMS NIH HHS SC1 GM140907NIGMS NIH HHS SC1GM140907NIMHD NIH HHS U54 MD007590
6 · The paper itself

Abstract

Prostate cancer is the most prevalent type of cancer in senior American men. Currently, the five-year survival rate after the initial diagnosis of prostate cancer is close to 100%. However, it is also the second leading cause of cancer death in senior men due to the dissemination of prostate cancer cells outside of the prostate causing growth in other organs, known as metastatic prostate cancer. The tumor microenvironment (TME) plays a critical role in the development, progression and metastasis of prostate cancer. One of the major components of the TME contains various types of immune cells, often recruited by cancer cells to the cancer formation areas. The interactions among prostate cancer cells and the infiltrating immune cells affect the outcome of prostate cancer. Here, we summarize the mechanisms various infiltrating immune cells use to regulate prostate cancer metastasis and possibly lead to the development of treatment strategies. Furthermore, the information here may also give rise to preventative strategies that focus on targeting the TME of prostate cancer patients.

Indexed as

immune cellsmetastasisprostate cancertherapytumor microenvironment

Identifiers

PMID36836690
PMCPMC9967893
OpenAlexW4318052301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.