Evidence map›Paper›PMID 36836688›Full record

ArticleLife (Basel, Switzerland)2023

Low-Dose Blue Light (420 nm) Reduces Metabolic Activity and Inhibits Proliferation of Human Dermal Fibroblasts.

Anne K E Brüning, Jennifer L Schiefer, Paul C Fuchs, Patrick Petzsch, Karl Köhrer, Christoph V Suschek, Ewa K Stürmer, Christian Opländer

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. 457 nm LED blue light inhibits oral squamous cell carcinoma cell proliferation via the PI3K/AKT pathway and autophagy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anne K E BrüningClinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center North Rhine-Westphalia, University Hospital, Ruhr-University Bochum, 32545 Bad Oeynhausen, Germany.
Jennifer L SchieferPlastic Surgery, Hand Surgery, Burn Center, Cologne-Merheim Hospital, Witten/Herdecke University, 51109 Cologne, Germany.
Paul C FuchsPlastic Surgery, Hand Surgery, Burn Center, Cologne-Merheim Hospital, Witten/Herdecke University, 51109 Cologne, Germany.ORCID 0000-0001-6399-9956
Patrick PetzschGenomics & Transcriptomics Laboratory, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.ORCID 0000-0002-8355-5524
Karl KöhrerGenomics & Transcriptomics Laboratory, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.ORCID 0000-0003-3644-2022
Christoph V SuschekDepartment for Orthopedics and Trauma Surgery, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.
Ewa K StürmerDepartment of Vascular Medicine, University Heart Center, University Medical Center Hamburg-Eppendorf (UKE), 20251 Hamburg, Germany.ORCID 0000-0003-4193-4857
Christian OpländerInstitute for Research in Operative Medicine (IFOM), Cologne-Merheim Medical Center, Witten/Herdecke University, 51109 Cologne, Germany.ORCID 0000-0001-7120-6063

Funding

German Research Foundation DFG OP 207/11-1
6 · The paper itself

Abstract

Hypertrophic scarring in burn wounds is caused by overactive fibroblasts and myofibroblasts. Blue light reveals wavelength- and dose-dependent antibacterial and antiproliferative effects and may serve as a therapeutic option against wound infection and fibrotic conditions. Therefore, we evaluated in this study the effects of single and multiple irradiations with blue light at 420 nm (BL

Indexed as

blue lightburnsfibrosisproliferationscarringwound infection

Identifiers

PMID36836688
PMCPMC9965217

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.