ReviewLife (Basel, Switzerland)2023
Endoscopic Vacuum Therapy (EVT) versus Self-Expandable Metal Stent (SEMS) for Anastomotic Leaks after Upper Gastrointestinal Surgery: Systematic Review and Meta-Analysis.
Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- VacStent as a novel therapeutic approach for esophageal perforations and anastomotic leaks- a systematic review of the literature.BMC surgery · 2025Pooled it
- Endoscopic treatment of anastomotic leakage after upper gastrointestinal surgery: endoscopic self-expandable metallic stent or endoscopic vacuum therapy?Clinical endoscopy · 2026Review
- Recurrent Cervical Esophageal Fistula and Retroesophageal Abscess Following Surgical Management of Zenker's Diverticulum.Journal of clinical medicine · 2026Article
- Rendezvous Stenting Technique for Anastomotic Leak After Total Gastrectomy: A Feasibility Study.Medicina (Kaunas, Lithuania) · 2026Article
- Endoluminal vacuum therapy for upper gastrointestinal leaks: safe, effective and minimally invasive - insights from a retrospective observational study.Surgical endoscopy · 2026Observational
- Endoscopic Management of Post-Bariatric Surgery Complications: Diagnostic Work-Up and Innovative Approaches for Leak, Fistula, and Stricture Management.Diagnostics (Basel, Switzerland) · 2026Review
- Management of Gastric Fistulas After Gastric Sleeve Using E-VAC Therapy.Diagnostics (Basel, Switzerland) · 2025Article
- Stenting Versus Endoscopic Vacuum Therapy for Anastomotic Leakage After Esophago-Gastric Surgery.Journal of clinical medicine · 2025Article
- Aortic hemorrhage following anastomotic leakage after esophagogastric surgery before and after implementation of endoscopic vacuum therapy.Surgical endoscopy · 2025Article
- Stents and Emerging Alternatives in Upper Gastrointestinal Endoscopy: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2025Review
- Comprehensive Umbrella Review of the Management of Esophageal Anastomotic Leaks.Journal of clinical medicine · 2025Review
- Endoscopic Treatment of Anastomotic Leakage in the Upper Gastrointestinal Tract.Visceral medicine · 2025Review
- Endoscopic vacuum therapy for gastrointestinal transmural defects: a literature review.Clinical endoscopy · 2025Review
- Multimodal therapeutic options for esophageal perforations-a single-center experience.Frontiers in surgery · 2025Article
- Vacuum stent: a game-changer in endoscopic multistep management of leakage following bariatric surgery.Endoscopy · 2024Article
- Microbiota profiling in esophageal diseases: Novel insights into molecular staining and clinical outcomes.Computational and structural biotechnology journal · 2024Review
- Article
- VAC-Stent in the Treatment of Post-Esophagectomy Anastomotic Leaks: A New "Kid on the Block" Who Marries the Best of Old Techniques-A Review.Journal of clinical medicine · 2024Review
- The Dual Lens of Endoscopy and Histology in the Diagnosis and Management of Eosinophilic Gastrointestinal Disorders-A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2024Review
- [Endoscopic Treatments in Perforation or Fistula in Upper Gastrointestinal Tract].The Korean journal of helicobacter and upper gastrointestinal research · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic treatment of post-esophagectomy/gastrectomy anastomotic dehiscence includes Self-Expandable Metal Stents (SEMS), which have represented the "gold standard" for many years, and Endoscopic Vacuum Therapy (EVT), which was recently introduced, showing promising results. The aim of the study was to compare outcomes of SEMS and EVT in the treatment of post-esophagectomy/gastrectomy anastomotic leaks, focusing on oncologic surgery.
methodsA systematic search was performed on Pubmed and Embase, identifying studies comparing EVT versus SEMS for the treatment of leaks after upper gastro-intestinal surgery for malignant or benign pathologies. The primary outcome was the rate of successful leak closure. A meta-analysis was conducted, performing an a priori-defined subgroup analysis for the oncologic surgery group.
resultsEight retrospective studies with 357 patients were eligible. Overall, the EVT group showed a higher success rate (odd ratio [OR] 2.58, 95% CI 1.43-4.66), a lower number of devices (pooled mean difference [pmd] 4.90, 95% CI 3.08-6.71), shorter treatment duration (pmd -9.18, 95% CI -17.05--1.32), lower short-term complication (OR 0.35, 95% CI 0.18-0.71) and mortality rates (OR 0.47, 95% CI 0.24-0.92) compared to stenting. In the oncologic surgery subgroup analysis, no differences in the success rate were found (OR 1.59, 95% CI 0.74-3.40, I
conclusionsOverall, EVT has been revealed to be more effective and less burdened by complications compared to stenting. In the oncologic surgery subgroup analysis, efficacy rates were similar between the two groups. Further prospective data need to define a unique management algorithm for anastomotic leaks.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.