Evidence map›Paper›PMID 36836611›Full record

ArticleLife (Basel, Switzerland)2023

Dynamics of Epiretinal Membrane Peeling under Perfluorocarbon Liquid Evaluated by Intraoperative OCT.

Tomaso Caporossi, Stefano Maria Picardi, Gloria Gambini, Antonio Baldascino, Matteo Mario Carlà, Andrea Molle, Alessandra Scampoli, Lorenzo Governatori, Stanislao Rizzo

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tomaso CaporossiVitreoretinal Surgery Unit, Fatebenefratelli Isola Tiberina Gemelli Isola Hospital, 00186 Rome, Italy.ORCID 0000-0002-6902-2983
Stefano Maria PicardiOphthalmology Unit, Catholic University Sacro Cuore, 20123 Rome, Italy.ORCID 0000-0003-0867-6411
Gloria GambiniOphthalmology Unit, Catholic University Sacro Cuore, 20123 Rome, Italy.
Antonio BaldascinoOphthalmology Unit, Catholic University Sacro Cuore, 20123 Rome, Italy.
Matteo Mario CarlàOphthalmology Unit, Catholic University Sacro Cuore, 20123 Rome, Italy.
Andrea MolleOphthalmology Unit, Catholic University Sacro Cuore, 20123 Rome, Italy.
Alessandra ScampoliVitreoretinal Surgery Unit, Fatebenefratelli Isola Tiberina Gemelli Isola Hospital, 00186 Rome, Italy.
Lorenzo GovernatoriVitreoretinal Surgery Unit, Fatebenefratelli Isola Tiberina Gemelli Isola Hospital, 00186 Rome, Italy.
Stanislao RizzoOphthalmology Unit, Catholic University Sacro Cuore, 20123 Rome, Italy.
Università Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study is to provide intraoperative data demonstrating a significant difference in the membrane peeling dynamics performed under a perfluorocarbon (PFCL) bubble, compared to normal balanced saline solution (BSS).

methodsThis is a prospective, interventional, single-center study on a series of 36 consecutive eyes of 36 patients affected by primary epiretinal membrane (ERM). Eighteen eyes underwent standard ERM peeling, while 18 eyes received a PFCL-assisted procedure. Intraoperative optical coherence tomography (iOCT) B-Scans were collected to evaluate the displacement angle (DA) between the underlying retinal plane and the flap of epiretinal tissue, along with the number of times the surgeon had to grab the flap during the intervention. Follow-up visits were carried out at postoperative week 1 and months 1, 3 and 6.

resultsThe mean DA was 164.8° ± 4.0 in the PFCL-assisted group and 119.7° ± 8.7 in the standard group, with a statistically significant difference between groups (

conclusionWe reported a statistically significant difference in the intraoperative peeling dynamics of the PFCL-assisted group, accounting for a decreased tendency in the tearing of the ERM flap and possibly reduced damage to the fiber layer, with equal effectiveness in improving visual function and foveal thickness.

Indexed as

dissociated optic nerve fiber layerepiretinal membraneintraoperative OCTmacular surgeryperfluorocarbon liquid

Identifiers

PMID36836611
PMCPMC9965307
OpenAlexW4316805764

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.