Evidence map›Paper›PMID 36836550›Full record

ArticleJournal of personalized medicine2023

Sex-Related Differences and Factors Associated with Peri-Procedural and 1 Year Mortality in Chronic Limb-Threatening Ischemia Patients from the CLIMATE Italian Registry.

Eugenio Martelli, Matilde Zamboni, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe M Sangiorgi, Mariangela V Puci, Allegra R Martelli, Teresa Messina, Paolo Frigatti and 70 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  12. Sex-specific associations between prolonged serum uric acid levels and risk of major adverse cardiovascular events.International journal of cardiology. Cardiovascular risk and prevention · 2024
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

80 authors at 20 institutions in 1 country.

Eugenio MartelliDepartment of General and Specialist Surgery Paride Stefanini, Faculty of Pharmacy and Medicine, Sapienza University of Rome, 155 viale del Policlinico, 00161 Rome, Italy.ORCID 0000-0001-5764-0082
Matilde ZamboniDivision of Vascular Surgery, Saint Martin Hospital, 22 viale Europa, 32100 Belluno, Italy.ORCID 0000-0002-6750-919X
Giovanni SotgiuClinical Epidemiology and Medical Statistics Unit, Department of Medicine, Surgery and Pharmacy, University of Sassari, viale San Pietro, 07100 Sassari, Italy.ORCID 0000-0002-1600-4474
Laura SaderiClinical Epidemiology and Medical Statistics Unit, Department of Medicine, Surgery and Pharmacy, University of Sassari, viale San Pietro, 07100 Sassari, Italy.ORCID 0000-0002-5131-9367
Massimo FedericiDepartment of Systems Medicine, University of Rome Tor Vergata, 1 viale Montpellier, 00133 Rome, Italy.
Giuseppe M SangiorgiDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 1 viale Montpellier, 00133 Rome, Italy.ORCID 0000-0001-5862-1967
Mariangela V PuciClinical Epidemiology and Medical Statistics Unit, Department of Medicine, Surgery and Pharmacy, University of Sassari, viale San Pietro, 07100 Sassari, Italy.ORCID 0000-0001-5656-6845
Allegra R MartelliMedicine and Surgery School of Medicine, Campus Bio-Medico University of Rome, 21 via À. del Portillo, 00128 Rome, Italy.
Teresa MessinaDivision of Anesthesia and Intensive Care of Organ Transplants, Umberto I Polyclinic University Hospital, 155 viale del Policlinico, 00161 Rome, Italy.
Paolo FrigattiDivisions of Vascular Surgery, S. Maria Misericordia University Hospital, 15 Piazzale Santa Maria della Misericordia, 33100 Udine, Italy.ORCID 0000-0002-4248-6673
Maria Pia BorrelliDivisions of Vascular Surgery, S. Maria Misericordia University Hospital, 15 Piazzale Santa Maria della Misericordia, 33100 Udine, Italy.
Carlo RuotoloDivisions of Vascular Surgery, Cardarelli Hospital, 9 Via A. Cardarelli, 80131 Naples, Italy.
Ilaria FicarelliDivisions of Vascular Surgery, Cardarelli Hospital, 9 Via A. Cardarelli, 80131 Naples, Italy.
Paolo RubinoDivisions of Vascular Surgery, Pugliese Ciaccio Hospital, 83 viale Pio X, 88100 Catanzaro, Italy.
Francesco PezzoDivisions of Vascular Surgery, Pugliese Ciaccio Hospital, 83 viale Pio X, 88100 Catanzaro, Italy.
Luciano CarbonariDivisions of Vascular Surgery, Riuniti University Hospitals, 71 via Conca, Torrette (AN), 60126 Ancona, Italy.
Andrea AngeliniDivisions of Vascular Surgery, Riuniti University Hospitals, 71 via Conca, Torrette (AN), 60126 Ancona, Italy.
Edoardo GaleazziDivisions of Vascular Surgery, Treviso Hospital, 1 piazzale del'Ospedale, 31100 Treviso, Italy.
Luca Calia Di PintoDivisions of Vascular Surgery, Treviso Hospital, 1 piazzale del'Ospedale, 31100 Treviso, Italy.
Franco M FioreDivisions of Vascular Surgery, SS. Annunziata Hospital, 31 via dei Vestini, 66100 Chieti, Italy.
Armando PalmieriDivisions of Vascular Surgery, SS. Annunziata Hospital, 31 via dei Vestini, 66100 Chieti, Italy.
Giorgio VentoruzzoDivisions of Vascular Surgery, San Donato Hospital, 20 via Pietro Nenni, 52100 Arezzo, Italy.
Giulia MazzitelliDivisions of Vascular Surgery, San Donato Hospital, 20 via Pietro Nenni, 52100 Arezzo, Italy.
Franco RagniDivisions of Vascular Surgery, San Matteo Polyclinic, 19 viale Camillo Golgi, 27100 Pavia, Italy.
Antonio BozzaniDivisions of Vascular Surgery, San Matteo Polyclinic, 19 viale Camillo Golgi, 27100 Pavia, Italy.ORCID 0000-0003-3274-6248
Enzo ForlitiDivisions of Vascular Surgery, Infermi Hospital, Via dei Ponderanesi 2, 13875 Ponderano, Italy.
Claudio CastagnoDivisions of Vascular Surgery, Infermi Hospital, Via dei Ponderanesi 2, 13875 Ponderano, Italy.
Pietro VolpeDivisions of Vascular Surgery, Bianchi-Melacrino-Morelli Hospital, 21 via G. Melacrino, 89124 Reggio di Calabria, Italy.
Mafalda MassaraDivisions of Vascular Surgery, Bianchi-Melacrino-Morelli Hospital, 21 via G. Melacrino, 89124 Reggio di Calabria, Italy.
Diego MoniaciDivisions of Vascular Surgery, San Giovanni Bosco Hospital, 3 piazza del Donatore di Sangue, 10154 Turin, Italy.ORCID 0000-0003-4324-6126
Elisa PagliassoDivisions of Vascular Surgery, San Giovanni Bosco Hospital, 3 piazza del Donatore di Sangue, 10154 Turin, Italy.
Tania PerettiDivisions of Vascular Surgery, San Giovanni Bosco Hospital, 3 piazza del Donatore di Sangue, 10154 Turin, Italy.
Mauro FerrariDivisions of Vascular Surgery, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 2 via Paradisa, 56124 Pisa, Italy.
Nicola TroisiDivisions of Vascular Surgery, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 2 via Paradisa, 56124 Pisa, Italy.ORCID 0000-0002-8779-9120
Piero ModugnoDivisions of Vascular Surgery, Gemelli Molise Hospital, 1 largo A. Gemelli, 86100 Campobasso, Italy.
Maurizio MaioranoDivisions of Vascular Surgery, Gemelli Molise Hospital, 1 largo A. Gemelli, 86100 Campobasso, Italy.
Umberto M BracaleDivisions of Vascular Surgery, Federico II Polyclinic, Department of Public Health and Residency Program in Vascular Surgery, University of Naples Federico II, 5 via S. Pansini, 80131 Naples, Italy.ORCID 0000-0001-9507-9791
Marco PanagrossoDivisions of Vascular Surgery, Federico II Polyclinic, Department of Public Health and Residency Program in Vascular Surgery, University of Naples Federico II, 5 via S. Pansini, 80131 Naples, Italy.
Mario MonacoDivisions of Vascular Surgery, Pineta Grande Hospital, Km. 30 via Domitiana, 81030 Castelvolturno, Italy.
Giovanni GiordanoDivisions of Vascular Surgery, Sanatrix Clinic, 31 via S. Domenico, 80127 Naples, Italy.
Giuseppe NatalicchioDivisions of Vascular Surgery, Venere Hospital, 1 via Ospedale di Venere, 70131 Bari, Italy.
Antonella BielloDivisions of Vascular Surgery, Venere Hospital, 1 via Ospedale di Venere, 70131 Bari, Italy.
Giovanni M CeloriaDivisions of Vascular Surgery, Sant'Andrea Hospital, 197 via Vittorio Veneto, 19121 La Spezia, Italy.
Alessio AmicoDivisions of Vascular Surgery, Sant'Andrea Hospital, 197 via Vittorio Veneto, 19121 La Spezia, Italy.
Mauro Di BartoloDivisions of Vascular Surgery, Sant'Andrea Hospital, 197 via Vittorio Veneto, 19121 La Spezia, Italy.ORCID 0000-0003-4510-3663
Massimiliano MartelliDivisions of Vascular Surgery, MultiMedica Hospital, 300 via Milenese, 20099 Sesto San Giovanni, Italy.
Roberta MunaóDivisions of Vascular Surgery, MultiMedica Hospital, 300 via Milenese, 20099 Sesto San Giovanni, Italy.
Davide RazzanoDivisions of Vascular Surgery, San Pio Hospital, 1 via dell'angelo, 82100 Benevento, Italy.
Giovanni ColacchioDivisions of Vascular Surgery, F.Miulli Hospital, Strada Prov. 127 Acquaviva-Santeramo Km. 4, 70021 Acquaviva delle Fonti, Italy.ORCID 0000-0003-0216-9005
Francesco BussettiDivisions of Vascular Surgery, F.Miulli Hospital, Strada Prov. 127 Acquaviva-Santeramo Km. 4, 70021 Acquaviva delle Fonti, Italy.
Gaetano LanzaDivisions of Vascular Surgery, Multimedica Hospital, 70 viale Piemonte, 21053 Castellanza, Italy.
Antonio CardiniDivisions of Vascular Surgery, Multimedica Hospital, 70 viale Piemonte, 21053 Castellanza, Italy.
Bartolomeo Di BenedettoDivisions of Vascular Surgery, Monaldi Hospital, via L. Bianchi, 84100 Naples, Italy.
Mario De LaurentisDivisions of Vascular Surgery, Monaldi Hospital, via L. Bianchi, 84100 Naples, Italy.
Maurizio TaurinoDivisions of Vascular Surgery, Department of Molecular and Clinical Medicine, Sapienza University of Rome, Giorgio Nicola Papanicolau, 00189 Rome, Italy.ORCID 0000-0001-5853-9410
Pasqualino SirignanoDepartment of General and Specialist Surgery Paride Stefanini, Faculty of Pharmacy and Medicine, Sapienza University of Rome, 155 viale del Policlinico, 00161 Rome, Italy.ORCID 0000-0002-1312-1915
Pierluigi CappielloDivisions of Vascular Surgery, San Carlo Hospital, via Potito Petrone, 85100 Potenza, Italy.
Andrea EspositoDivisions of Vascular Surgery, San Carlo Hospital, via Potito Petrone, 85100 Potenza, Italy.
Santi TrimarchiDivisions of Vascular Surgery, Department of Clinical and Community Sciences, University of Milan, 19 via della Commenda, 20122 Milan, Italy.
Silvia RomagnoliDivisions of Vascular Surgery, Maggiore Polyclinic Hospital Ca' Granda IRCCS and Foundation, 35 via Francesco Sforza, 20122 Milan, Italy.
Andrea PadricelliDivision of Vascular Surgery, Department of Cardiovascular Sciences, S. Anna and S. Sebastiano Hospital, via F. Palasciano, 81100 Caserta, Italy.
Giorgio GiudiceDivision of Vascular Surgery, Department of Cardiovascular Sciences, S. Anna and S. Sebastiano Hospital, via F. Palasciano, 81100 Caserta, Italy.
Adolfo CrinisioDivisions of Vascular Surgery, Salus Clinic, 4 via F. Confalonieri, 84091 Battipaglia, Italy.
Giovanni Di NardoDivisions of Vascular Surgery, Salus Clinic, 4 via F. Confalonieri, 84091 Battipaglia, Italy.
Giuseppe BattagliaDivisions of Vascular Surgery, San Marco Hospital, viale Carlo Azeglio Ciampi, 95121 Catania, Italy.
Rosario TringaleDivisions of Vascular Surgery, San Marco Hospital, viale Carlo Azeglio Ciampi, 95121 Catania, Italy.
Salvatore De VivoDivisions of Vascular Surgery, Pellegrini Hospital, 41 via Portamedina alla Pignasecca, 80134 Naples, Italy.
Rita CompagnaDivisions of Vascular Surgery, Pellegrini Hospital, 41 via Portamedina alla Pignasecca, 80134 Naples, Italy.
Valerio S TolvaDivisions of Vascular Surgery, Niguarda Hospital, Piazza dell'Ospedale Maggiore 3, 20161 Milan, Italy.ORCID 0000-0002-4642-0727
Ilenia D'AlessioDivisions of Vascular Surgery, Niguarda Hospital, Piazza dell'Ospedale Maggiore 3, 20161 Milan, Italy.
Ruggiero CurciDivisions of Vascular Surgery, Maggiore Hospital, 10 Piazza Ospitale, 26900 Lodi, Italy.
Simona GiovannettiDivisions of Vascular Surgery, Maggiore Hospital, 10 Piazza Ospitale, 26900 Lodi, Italy.
Giuseppe D'ArrigoDivisions of Vascular Surgery, Garibaldi-Nesima Hospital, 636 via Palermo, 95122 Catania, Italy.
Giusi BasileDivisions of Vascular Surgery, Garibaldi-Nesima Hospital, 636 via Palermo, 95122 Catania, Italy.
Dalmazio FrigerioDivisions of Vascular Surgery, Vimercate Hospital, 10 via Cosma e Damiano, 20871 Vimercate, Italy.
Gian Franco VeraldiDivisions of Vascular Surgery, University Hospital Pietro Confortini, 1 Piazzale Aristide Stefani, 37126 Verona, Italy.
Luca MezzettoDivisions of Vascular Surgery, University Hospital Pietro Confortini, 1 Piazzale Aristide Stefani, 37126 Verona, Italy.ORCID 0000-0002-6284-1740
Arnaldo IppolitiDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 1 viale Montpellier, 00133 Rome, Italy.
Fabio M OddiDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 1 viale Montpellier, 00133 Rome, Italy.ORCID 0000-0001-8081-807X
Alberto M SettembriniDivisions of Vascular Surgery, Maggiore Polyclinic Hospital Ca' Granda IRCCS and Foundation, 35 via Francesco Sforza, 20122 Milan, Italy.ORCID 0000-0001-7802-1969
MultiMedica · ITUniversity of Rome Tor Vergata · ITOspedale San Giovanni Bosco · ITPoliclinico Umberto I · ITUniversity of Sassari · ITAzienda ospedaliera "Bianchi-Melacrino-Morelli" · ITAzienda Ospedaliera Pugliese Ciaccio · ITCa' Foncello Hospital · ITFederico II University Hospital · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITOspedale Antonio Cardarelli · ITOspedale Civile di Venezia · ITOspedale degli Infermi · ITOspedale dei Pellegrini · ITOspedale Garibaldi · ITOspedale Maggiore · ITOspedale Monaldi · ITOspedale San Carlo · ITOspedale San Donato · ITOspedale Santa Maria della Misericordia di Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdentifying sex-related differences/variables associated with 30 day/1 year mortality in patients with chronic limb-threatening ischemia (CLTI).

methodsMulticenter/retrospective/observational study. A database was sent to all the Italian vascular surgeries to collect all the patients operated on for CLTI in 2019. Acute lower-limb ischemia and neuropathic-diabetic foot are not included. FOLLOW-UP: One year. Data on demographics/comorbidities, treatments/outcomes, and 30 day/1 year mortality were investigated.

resultsInformation on 2399 cases (69.8% men) from 36/143 (25.2%) centers. Median (IQR) age: 73 (66-80) and 79 (71-85) years for men/women, respectively (

conclusionWomen exhibit fewer comorbidities but are struck by CLTI when over 75, a factor associated with short- and mid-term mortality, explaining why mortality does not statistically differ between the sexes.

Indexed as

agechronic limb-threatening ischemialimb salvageoutcomesex

Identifiers

PMID36836550
PMCPMC9959358
OpenAlexW4320493129

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.