ReviewJournal of personalized medicine2023
Clinical Presentation and Risk Factors of Infective Endocarditis in the Elderly: A Systematic Review.
Review in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Changing Patterns in Infective Endocarditis: A Contemporary Epidemiological Perspective.Pathogens (Basel, Switzerland) · 2026Review
- A Devastating Separation: A Case of Prosthetic Valve Embolization.The American journal of forensic medicine and pathology · 2026Article
- Infective Endocarditis: A Contemporary Review of Epidemiology, Diagnosis, and Management.Antibiotics (Basel, Switzerland) · 2026Review
- Levofloxacin-Resistant Streptococcus gordonii Infective Endocarditis in an Elderly Patient: A Case Report.Cureus · 2026Article
- Age and New York Heart Association Class as Predictors of Surgical Outcomes in Patients With Infective Endocarditis.Cureus · 2025Article
- Mapping Review of the Correlations Between Periodontitis, Dental Caries, and Endocarditis.Dentistry journal · 2025Review
- Risk factors for endogenous endophthalmitis in infectious endocarditis patients.Eye (London, England) · 2025Article
- Unexpected Infective Endocarditis: Towards a New Alert for Clinicians.Journal of clinical medicine · 2024Review
- The Glasgow prognosis score is unsuitable for stroke prediction in infectious endocarditis.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Membranoproliferative Glomerulonephritis due toGlomerular diseasesArticle
- [Comparison of the epidemiological, clinical and diagnostic characteristics of infective endocarditis of native and prosthetic valves in a Peruvian reference center].Archivos peruanos de cardiologia y cirugia cardiovascularArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infective endocarditis (IE) is a bacterial infection with high morbidity and mortality rates, particularly among the elderly. This systematic review was conducted to determine the clinical characteristics of IE in older adults and the risk factors that could lead to adverse outcomes. The research employed three databases (PubMed, Wiley, and Web of Science), with a primary search for studies that have described cases of IE in patients older than 65 years. From a total of 555 articles, 10 were selected for inclusion in the current study, comprising a total of 2222 patients with a confirmed diagnosis of IE. The primary findings were an increased incidence of staphylococcal and streptococcal infections (33.4% and32.0%, respectively), an increased prevalence of comorbidities, namely, cardiovascular disease, diabetes, and cancer, and a significantly greater mortality risk than the younger group. Regarding mortality risks, the pooled odds ratio for cardiac disorders was OR = 3.81, septic shock OR = 8.22, renal complications OR = 3.75, and advancing age OR = 3.54 were most frequently mentioned. Taking into consideration the fact that the majority of the elderly population suffers from significant complications and is unable to undergo surgery due to an increased risk of complications after the procedure, it is imperative that effective treatment methods should be investigated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.