Evidence map›Paper›PMID 36836442›Full record

ArticleJournal of personalized medicine2023

Differences and Similarities in Empathy Deficit and Its Neural Basis between Logopenic and Amnesic Alzheimer's Disease.

Giulia Giacomucci, Cristina Polito, Valentina Berti, Sonia Padiglioni, Giulia Galdo, Salvatore Mazzeo, Enrico Bergamin, Valentina Moschini, Carmen Morinelli, Claudia Nuti and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Empathy in primary progressive aphasia: Neural signatures and longitudinal trajectories.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Review
  3. Personalized and Precision Medicine 2022.Journal of personalized medicine · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Giulia GiacomucciDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-8711-331X
Cristina PolitoIRCCS Fondazione Don Carlo Gnocchi, 50143 Florence, Italy.
Valentina BertiDepartment of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, 50134 Florence, Italy.ORCID 0000-0001-9947-6559
Sonia PadiglioniRegional Referral Centre for Relational Criticalities-Tuscany Region, 50134 Florence, Italy.
Giulia GaldoDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.
Salvatore MazzeoDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.ORCID 0000-0001-5985-5060
Enrico BergaminUniversity of Florence, 50134 Florence, Italy.
Valentina MoschiniSOD Neurologia I, Dipartmento Neuromuscolo-Scheletrico e degli Organi di Senso, AOU Careggi, 50134 Florence, Italy.
Carmen MorinelliSOD Neurologia I, Dipartmento Neuromuscolo-Scheletrico e degli Organi di Senso, AOU Careggi, 50134 Florence, Italy.
Claudia NutiUniversity of Florence, 50134 Florence, Italy.
Maria Teresa De CristofaroNuclear Medicine Unit, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy.
Assunta IngannatoDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.ORCID 0000-0003-4955-0321
Silvia BagnoliDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.
Benedetta NacmiasDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.ORCID 0000-0001-9338-9040
Sandro SorbiDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.
Valentina BessiDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-6176-3584
University of Florence · ITDon Carlo Gnocchi Foundation · ITAzienda Ospedaliero-Universitaria Careggi · ITGruppo Italiano per il Trapianto di Midollo Osseo · ITRegione Toscana

Funding

Ateneo Università di Firenze RICATEN22
6 · The paper itself

Abstract

The aims of the study were to assess empathy deficit and neuronal correlates in logopenic primary progressive aphasia (lv-PPA) and compare these data with those deriving from amnesic Alzheimer's disease (AD). Eighteen lv-PPA and thirty-eight amnesic AD patients were included. Empathy in both cognitive and affective domains was assessed by Informer-rated Interpersonal Reactivity Index (perspective taking, PT, and fantasy, FT, for cognitive empathy; empathic concern, EC, and personal distress, PD, for affective empathy) before (T0) and after (T1) cognitive symptoms' onset. Emotion recognition was explored through the Ekman 60 Faces Test. Cerebral FDG-PET was used to explore neural correlates underlying empathy deficits. From T0 to T1, PT scores decreased, and PD scores increased in both lv-PPA (PT z = -3.43,

Indexed as

Alzheimer’s diseaseempathylogopenic variant primary progressive aphasia

Identifiers

PMID36836442
PMCPMC9966635
OpenAlexW4318053858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.