Evidence map›Paper›PMID 36836437›Full record

ArticleJournal of personalized medicine2023

End-to-End Deep-Learning-Based Diagnosis of Benign and Malignant Orbital Tumors on Computed Tomography Images.

Ji Shao, Jiazhu Zhu, Kai Jin, Xiaojun Guan, Tianming Jian, Ying Xue, Changjun Wang, Xiaojun Xu, Fengyuan Sun, Ke Si and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ji ShaoDepartment of Ophthalmology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.
Jiazhu ZhuCenter for Neuroscience and Department of Neurobiology of the Second Affiliated Hospital, State Key Laboratory of Modern Optical Instrumentation, Zhejiang University School of Medicine, Hangzhou 310027, China.
Kai JinDepartment of Ophthalmology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.ORCID 0000-0003-4369-2417
Xiaojun GuanDepartment of Radiology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.ORCID 0000-0003-2313-4477
Tianming JianTianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin Medical University, Tianjin 300203, China.
Ying XueCenter for Neuroscience and Department of Neurobiology of the Second Affiliated Hospital, State Key Laboratory of Modern Optical Instrumentation, Zhejiang University School of Medicine, Hangzhou 310027, China.
Changjun WangDepartment of Ophthalmology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.
Xiaojun XuDepartment of Radiology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.
Fengyuan SunTianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin Medical University, Tianjin 300203, China.
Ke SiCenter for Neuroscience and Department of Neurobiology of the Second Affiliated Hospital, State Key Laboratory of Modern Optical Instrumentation, Zhejiang University School of Medicine, Hangzhou 310027, China.
Wei GongCenter for Neuroscience and Department of Neurobiology of the Second Affiliated Hospital, State Key Laboratory of Modern Optical Instrumentation, Zhejiang University School of Medicine, Hangzhou 310027, China.
Juan YeDepartment of Ophthalmology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.
Second Affiliated Hospital of Zhejiang University · CNTianjin Medical University Eye Hospital · CN

Funding

National Natural Science Foundation Regional Innovation and Development Joint Fund U20A20386Natural Science Foundation of Zhejiang Province LR20F050002the National Key Research and Development Program of China 2019YFC0118401the National Natural Science Foundation of China 61975178Zhejiang Provincial Key Research and Development Plan 2019C03020
6 · The paper itself

Abstract

Determining the nature of orbital tumors is challenging for current imaging interpretation methods, which hinders timely treatment. This study aimed to propose an end-to-end deep learning system to automatically diagnose orbital tumors. A multi-center dataset of 602 non-contrast-enhanced computed tomography (CT) images were prepared. After image annotation and preprocessing, the CT images were used to train and test the deep learning (DL) model for the following two stages: orbital tumor segmentation and classification. The performance on the testing set was compared with the assessment of three ophthalmologists. For tumor segmentation, the model achieved a satisfactory performance, with an average dice similarity coefficient of 0.89. The classification model had an accuracy of 86.96%, a sensitivity of 80.00%, and a specificity of 94.12%. The area under the receiver operating characteristics curve (AUC) of the 10-fold cross-validation ranged from 0.8439 to 0.9546. There was no significant difference on diagnostic performance of the DL-based system and three ophthalmologists (

Indexed as

classificationdeep learninghemangiomalymphomasegmentation

Identifiers

PMID36836437
PMCPMC9960119
OpenAlexW4317907194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.