Evidence map›Paper›PMID 36836355›Full record

ArticleJournal of fungi (Basel, Switzerland)2023

Antifungal Activity of Isavuconazole and Comparator Agents against Contemporaneous Mucorales Isolates from USA, Europe, and Asia-Pacific.

Cecilia G Carvalhaes, Paul R Rhomberg, Michael D Huband, Michael A Pfaller, Mariana Castanheira

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Determination of Potential Inhibitors againstCurrent pharmaceutical design · 2026
    Review
  5. Mucormycosis.Infectious disease clinics of North America · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cecilia G CarvalhaesJMI Laboratories, 345 Beaver Kreek Centre, North Liberty, IA 52317, USA.ORCID 0000-0002-2734-3754
Paul R RhombergJMI Laboratories, 345 Beaver Kreek Centre, North Liberty, IA 52317, USA.
Michael D HubandJMI Laboratories, 345 Beaver Kreek Centre, North Liberty, IA 52317, USA.
Michael A PfallerJMI Laboratories, 345 Beaver Kreek Centre, North Liberty, IA 52317, USA.
Mariana CastanheiraJMI Laboratories, 345 Beaver Kreek Centre, North Liberty, IA 52317, USA.
JMI Laboratories · US

Funding

Pfizer (USA) 21-PZR-09
6 · The paper itself

Abstract

Isavuconazole is the only US FDA-approved antifungal for treating invasive mucormycosis. We evaluated isavuconazole activity against a global collection of Mucorales isolates. Fifty-two isolates were collected during 2017-2020 from hospitals located in the USA, Europe, and the Asia-Pacific. Isolates were identified by MALDI-TOF MS and/or DNA sequencing and susceptibility tested by the broth microdilution method following CLSI guidelines. Isavuconazole (MIC

Indexed as

antifungal activityazolesLichtheimiamucormycosisRhizomucorRhizopus

Identifiers

PMID36836355
PMCPMC9960003
OpenAlexW4320496801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.