Evidence map›Paper›PMID 36836213›Full record

ArticleJournal of clinical medicine2023

High-Flow Nasal Cannula Oxygen Therapy versus Non-Invasive Ventilation in AIDS Patients with Acute Respiratory Failure: A Randomized Controlled Trial.

Jingjing Hao, Jingyuan Liu, Lin Pu, Chuansheng Li, Ming Zhang, Jianbo Tan, Hongyu Wang, Ningning Yin, Yao Sun, Yufeng Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Jingjing HaoDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.ORCID 0000-0001-9347-1351
Jingyuan LiuDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Lin PuDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Chuansheng LiDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Ming ZhangDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Jianbo TanDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Hongyu WangDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Ningning YinDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Yao SunDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Yufeng LiuDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Hebing GuoDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Ang LiDepartment of Critical Care Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Capital Medical University · CN

Funding

Capital Development Special Program of Beijing Hospital Authority, China 2018-1-2171
6 · The paper itself

Abstract

backgroundAcute respiratory failure (ARF) remains the most common diagnosis for intensive care unit (ICU) admission in acquired immunodeficiency syndrome (AIDS) patients.

methodsWe conducted a single-center, prospective, open-labeled, randomized controlled trial at the ICU, Beijing Ditan Hospital, China. AIDS patients with ARF were enrolled and randomly assigned in a 1:1 ratio to receive either high-flow nasal cannula (HFNC) oxygen therapy or non-invasive ventilation (NIV) immediately after randomization. The primary outcome was the need for endotracheal intubation on day 28.

results120 AIDS patients were enrolled and 56 patients in the HFNC group and 57 patients in the NIV group after secondary exclusion. Pneumocystis pneumonia (PCP) was the main etiology for ARF (94.7%). The intubation rates on day 28 were similar to HFNC and NIV (28.6% vs. 35.1%,

conclusionsAmong AIDS patients with ARF, there was no statistical significance of the intubation rate between HFNC and NIV. HFNC had better tolerance and device comfort, fewer airway care interventions, and a lower respiratory rate than NIV. CLINICAL TRIAL NUMBER: Chictr.org (ChiCTR1900022241).

Indexed as

acquired immunodeficiency syndromeacute respiratory failurehigh-flow nasal cannula oxygen therapynon-invasive ventilation

Identifiers

PMID36836213
PMCPMC9967185
OpenAlexW4321373376

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.