Evidence map›Paper›PMID 36836202›Full record

ArticleJournal of clinical medicine2023

Clinical Significance of Trace Element Zinc in Patients with Chronic Kidney Disease.

Hirotaka Fukasawa, Ryuichi Furuya, Mai Kaneko, Daisuke Nakagami, Yuri Ishino, Shuhei Kitamoto, Kyosuke Omata, Hideo Yasuda

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  15. Serum zinc levels in hemodialysis and peritoneal dialysis patients: A retrospective observational study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hirotaka FukasawaRenal Division, Department of Internal Medicine, Iwata City Hospital, Iwata 438-8550, Shizuoka, Japan.
Ryuichi FuruyaRenal Division, Department of Internal Medicine, Iwata City Hospital, Iwata 438-8550, Shizuoka, Japan.
Mai KanekoRenal Division, Department of Internal Medicine, Iwata City Hospital, Iwata 438-8550, Shizuoka, Japan.
Daisuke NakagamiRenal Division, Department of Internal Medicine, Iwata City Hospital, Iwata 438-8550, Shizuoka, Japan.
Yuri IshinoRenal Division, Department of Internal Medicine, Iwata City Hospital, Iwata 438-8550, Shizuoka, Japan.
Shuhei KitamotoRenal Division, Department of Internal Medicine, Iwata City Hospital, Iwata 438-8550, Shizuoka, Japan.
Kyosuke OmataRenal Division, Department of Internal Medicine, Iwata City Hospital, Iwata 438-8550, Shizuoka, Japan.
Hideo YasudaFirst Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu 431-3192, Shizuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The trace element zinc is essential for diverse physiological processes in humans. Zinc deficiency can impair growth, skin reproduction, immune function, maintenance of taste, glucose metabolism, and neurological function. Patients with chronic kidney disease (CKD) are susceptible to zinc deficiency, which is associated with erythropoiesis-stimulating agent (ESA) hypo-responsive anemia, nutritional problems, and cardiovascular diseases as well as non-specific symptoms such as dermatitis, prolonged wound healing, taste disturbance, appetite loss, or cognitive decline. Thus, zinc supplementation may be useful for the treatment of its deficiency, although it often causes copper deficiency, which is characterized by several severe disorders including cytopenia and myelopathy. In this review article, we mainly discuss the significant roles of zinc and the association between zinc deficiency and the pathogenesis of complications in patients with CKD.

Indexed as

anemiacardiovascular diseasechronic kidney diseasecoppernutritionzinc

Identifiers

PMID36836202
PMCPMC9964431

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.