Evidence map›Paper›PMID 36836076›Full record

ArticleJournal of clinical medicine2023

Lung Injury in COVID-19 Has Pulmonary Edema as an Important Component and Treatment with Furosemide and Negative Fluid Balance (NEGBAL) Decreases Mortality.

Jose L Francisco Santos, Patricio Zanardi, Veronica Alo, Vanina Dos Santos, Leonardo Bovone, Marcelo Rodriguez, Federico Magdaleno, Virginia De Langhe, Andrea Villoldo, Romina Martinez Souvielle and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Jose L Francisco SantosIntensive Care Unit, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.ORCID 0000-0001-6739-5156
Patricio ZanardiIntensive Care Unit, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.
Veronica AloIntensive Care Unit, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.
Vanina Dos SantosIntensive Care Unit, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.
Leonardo BovoneIntensive Care Unit, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.
Marcelo RodriguezCardiology Service, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.
Federico MagdalenoDiagnostic Imaging Service, Hospital Privado del Sur. Bahía Blanca, Buenos Aires 8000, Argentina.
Virginia De LangheDiagnostic Imaging Service, Hospital Privado del Sur. Bahía Blanca, Buenos Aires 8000, Argentina.
Andrea VilloldoIntensive Care Unit, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.
Romina Martinez SouvielleIntensive Care Unit, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.
Julieta AlconcherDiagnostic Imaging Service, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.
Diego QuirosDiagnostic Imaging Service, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.
Claudio MilicchioDiagnostic Imaging Service, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.
Eduardo Garcia SaizDiagnostic Imaging Service, Clínica Colón, Mar del Plata, Buenos Aires 7600, Argentina.
Centro Científico Tecnológico Mar del Plata · ARHospital Privado · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SARS-CoV2 promotes dysregulation of Renin-Angiotensin-Aldosterone. The result is excessive retention of water, producing a state of noxious hypervolemia. Consequently, in COVID-19 injury lung is pulmonary edema. Our report is a case-control study, retrospective. We included 116 patients with moderate-severe COVID-19 lung injury. A total of 58 patients received standard care (Control group). A total of 58 patients received a standard treatment with a more negative fluid balance (NEGBAL group), consisting of hydric restriction and diuretics. Analyzing the mortality of the population studied, it was observed that the NEGBAL group had lower mortality than the Control group,

Indexed as

COVID-19diureticedemafurosemideNEGBALvolume overload

Identifiers

PMID36836076
PMCPMC9966668
OpenAlexW4321096998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.