Evidence map›Paper›PMID 36836065›Full record

ArticleJournal of clinical medicine2023

Prevalence of Sarcopenia in Knee Osteoarthritis: A Systematic Review and Meta-Analysis.

Francesco Pegreffi, Alice Balestra, Orazio De Lucia, Lee Smith, Mario Barbagallo, Nicola Veronese

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Prevalence of osteosarcopenia in patients with end-stage knee OA who underwent total knee arthroplasty.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Knee Health Is a Major Determinant of Mobility Across the Healthspan.Journal of functional morphology and kinesiology · 2025
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Francesco PegreffiDipartimento di Scienze per la Qualità della Vita-QUVI, Università di Bologna, 47921 Rimini, Italy.ORCID 0000-0002-6788-6040
Alice BalestraDipartimento di Scienze per la Qualità della Vita-QUVI, Università di Bologna, 47921 Rimini, Italy.
Orazio De LuciaUnit of Clinical Rheumatology, Department of Rheumatology and Medical Sciences, ASST Centro Traumatologico Ortopedico G. Pini-CTO, 20122 Milan, Italy.ORCID 0000-0003-2304-6661
Lee SmithCentre for Health, Performance and Wellbeing, Anglia Ruskin University, Cambridge CB1 1PT, UK.ORCID 0000-0002-5340-9833
Mario BarbagalloDepartment of Internal Medicine, Geriatrics Section, University of Palermo, 90128 Palermo, Italy.ORCID 0000-0002-1349-6530
Nicola VeroneseDepartment of Internal Medicine, Geriatrics Section, University of Palermo, 90128 Palermo, Italy.ORCID 0000-0002-9328-289X
University of Bologna · ITUniversity of Palermo · ITAnglia Ruskin University · GBIstituto Ortopedico Gaetano Pini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An association between knee osteoarthritis (OA) and sarcopenia has been proposed, but the evidence is controversial, with the recent literature showing disparate results. Therefore, we aimed to perform a systematic review and meta-analysis to evaluate the prevalence of sarcopenia in knee OA patients compared to people not affected by this condition. We searched several databases until 22 February 2022. The data regarding prevalence were summarized using odds ratios (ORs) with their 95% confidence intervals (CIs). Among the 504 papers initially screened, 4 were included for a total of 7495 participants with a mean age of 68.4 years, who were mainly females (72.4%). The prevalence of sarcopenia in people with knee OA was 45.2%, whilst, in the controls, it was 31.2%. Pooling the data of the studies included that the prevalence of sarcopenia in knee OA was more than two times higher than in the control group (OR = 2.07; 95%CI: 1.43-3.00; I

Indexed as

knee osteoarthritismeta-analysissarcopenia

Identifiers

PMID36836065
PMCPMC9963114
OpenAlexW4320918465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.