Evidence map›Paper›PMID 36836015›Full record

ArticleJournal of clinical medicine2023

Effect of Pemafibrate on Hemorheology in Patients with Hypertriglyceridemia and Aggravated Blood Fluidity Associated with Type 2 Diabetes or Metabolic Syndrome.

Tomohiro Iwakura, Takanori Yasu, Takashi Tomoe, Asuka Ueno, Takushi Sugiyama, Naoyuki Otani, Shinya Kawamoto, Hiroyuki Nakajima

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tomohiro IwakuraDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University, Nikko Medical Center, 145-1 Moritomo, Nikko 321-2593, Tochigi, Japan.ORCID 0000-0003-0733-0099
Takanori YasuDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University, Nikko Medical Center, 145-1 Moritomo, Nikko 321-2593, Tochigi, Japan.ORCID 0000-0002-1940-2347
Takashi TomoeDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University, Nikko Medical Center, 145-1 Moritomo, Nikko 321-2593, Tochigi, Japan.
Asuka UenoDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University, Nikko Medical Center, 145-1 Moritomo, Nikko 321-2593, Tochigi, Japan.
Takushi SugiyamaDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University, Nikko Medical Center, 145-1 Moritomo, Nikko 321-2593, Tochigi, Japan.
Naoyuki OtaniDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University, Nikko Medical Center, 145-1 Moritomo, Nikko 321-2593, Tochigi, Japan.
Shinya KawamotoDepartment of Cardiovascular Medicine and Nephrology, Dokkyo Medical University, Nikko Medical Center, 145-1 Moritomo, Nikko 321-2593, Tochigi, Japan.
Hiroyuki NakajimaDepartment of Cardiovascular Surgery, Yamanashi University, 1110 Shimokato, Chuo-shi 409-3839, Yamanashi, Japan.
Dokkyo Medical University · JPUniversity of Yamanashi Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent high serum triglyceride (TG) and free fatty acid (FFA) levels, which are common in metabolic syndrome and type 2 diabetes, are risk factors for cardiovascular events because of exacerbated hemorheology. To explore the effects of pemafibrate, a selective peroxisome proliferator-activated receptor alpha modulator, on hemorheology, we performed a single-center, nonrandomized, controlled study in patients with type 2 diabetes (HbA1c 6-10%) or metabolic syndrome, with fasting TG levels of ≥ 150 mg/dL and a whole blood transit time of > 45 s on a microarray channel flow analyzer (MCFAN). Patients were divided into a study group, receiving 0.2 mg/day of pemafibrate (

Indexed as

diabetes mellitusfree fatty acidmetabolic syndromemicrocirculationrheologytriglyceride

Identifiers

PMID36836015
PMCPMC9962113
OpenAlexW4320496012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.