Evidence map›Paper›PMID 36835962›Full record

ArticleJournal of clinical medicine2023

The Impact of Pre-Chemotherapy Body Composition and Immunonutritional Markers on Chemotherapy Adherence in Stage III Colorectal Cancer Patients.

Soohyeon Lee, Dong Hyun Kang, Tae Sung Ahn, Seung Soo Kim, Jong Hyuk Yun, Hyun Jung Kim, Seoung Hee Seo, Tae Wan Kim, Hye Jeong Kong, Moo Jun Baek

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Soohyeon LeeDepartment of Surgery, Soonchunhyang University College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Republic of Korea.ORCID 0000-0002-6423-4434
Dong Hyun KangDepartment of Surgery, Soonchunhyang University College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Republic of Korea.
Tae Sung AhnDepartment of Surgery, Soonchunhyang University College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Republic of Korea.
Seung Soo KimDepartment of Radiology, Soonchunhyang University College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Republic of Korea.ORCID 0000-0002-1763-8217
Jong Hyuk YunDepartment of Surgery, Soonchunhyang University College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Republic of Korea.ORCID 0000-0002-8746-4945
Hyun Jung KimDepartment of Surgery, Soonchunhyang University College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Republic of Korea.
Seoung Hee SeoDepartment of Surgery, Soonchunhyang University College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Republic of Korea.ORCID 0000-0002-6859-3223
Tae Wan KimDepartment of Medical Life Science, Soonchunhyang University, Asan 31538, Republic of Korea.
Hye Jeong KongDepartment of Medical Life Science, Soonchunhyang University, Asan 31538, Republic of Korea.
Moo Jun BaekDepartment of Surgery, Soonchunhyang University College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Republic of Korea.
Soonchunhyang University · KR

Funding

National Research Foundation of Korea 2019M3E5D1A02069058Soonchunhyang University Research Fund 2019R1I1A3A01061911
6 · The paper itself

Abstract

Patients with colorectal cancer (CRC) often fail to complete full-course chemotherapy with a standard dose due to various reasons. This study aimed to determine whether body composition affects chemotherapy adherence in patients with CRC. The medical records of 107 patients with stage III CRC who underwent adjuvant folinic acid, fluorouracil and oxaliplatin (FOLFOX) chemotherapy at a single center between 2014 and 2018 were analyzed retrospectively. Blood test results for selected immunonutritional markers were analyzed and body composition was measured through computed tomography. Univariate and multivariate analyses were performed on low and high relative dose intensity (RDI) groups, based on an RDI of 0.85. In the univariate analysis, a higher skeletal muscle index was correlated with a higher RDI (

Indexed as

body compositionchemotherapy adherencecolorectal cancerrelative dose intensity

Identifiers

PMID36835962
PMCPMC9962672
OpenAlexW4320494109

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.