ArticleJournal of clinical medicine2023
Sex Differences in Motor and Non-Motor Symptoms among Spanish Patients with Parkinson's Disease.
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Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27citing papers in PubMed
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Who cites it
27 citing papers in PubMed, 24 citations in OpenAlex.
- The effects of safinamide according to gender in Chinese parkinsonian patients.Scientific reports · 2023Trial
- Healthy rural living: a misplaced optimism? : District-level agricultural index and Parkinson's disease risk in Austria.Wiener klinische Wochenschrift · 2026Article
- Online Comprehensive Care Therapy Complementary Program Improves Quality of Life in People with Parkinson's Disease.Brain sciences · 2026Article
- Sex difference in Parkinson's disease hospitalization rates in Brazil (2010-2024).BMC neurology · 2026Article
- Sex Differences in the Treatment of People with Parkinson's Disease with a Device-Aided Therapy: A Prospective Real-World Study.Medical sciences (Basel, Switzerland) · 2026Observational
- Gender differences in non-motor symptoms in Parkinson's disease: a multicenter longitudinal study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Differential psychosocial burden in parkinson's disease: a gender-based comparison.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Sex differences in the severity of non-motor symptoms in Parkinson's disease: a systematic review and meta-analysis.NPJ Parkinson's disease · 2026Article
- Deep Brain Stimulation for Movement Disorders in Spain: Temporal Trends, Complications, and Sex-Related Disparities (2002-2019).Healthcare (Basel, Switzerland) · 2026Article
- Clinical and autonomic correlates of chronic Sialorrhea in Parkinson's disease: a questionnaire-based study with cluster analysis of autonomic and dysphagia burden.Clinical parkinsonism & related disorders · 2026Article
- Factors associated with self- perceived speech impairment inFrontiers in aging neuroscience · 2026Article
- Sex differences in levodopa pharmacokinetics in early Parkinson's disease: implications on levodopa-related complications.Frontiers in pharmacology · 2026Article
- Prevalence of Probable REM Sleep Behavior Disorder in Essential Tremor.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- Factors Associated With Improved Physical Performance in Individuals With Parkinson's Disease Using the Fisior® Sequential Square Mat Walking Training Program: A Secondary Gender-Stratified Analysis of a Randomized Controlled Trial.Journal of central nervous system disease · 2026Article
- Sex-dependent immune activation shapes disease progression in a model of Parkinson's disease.Biology of sex differences · 2025Article
- Demographic and Clinical Profiles of Parkinson's Disease in India: Observations from a Nation-Wide Multicenter Study.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Effect of Safinamide on Non-Motor Symptoms and Quality of Life in Parkinson's Disease Patients According to Sex, Age, Disease Duration and Levodopa Equivalent Daily Dose.Brain sciences · 2025Article
- Chronic stress induces depression-like behaviors and Parkinsonism via upregulating α-synuclein.NPJ Parkinson's disease · 2025Article
- Explaining facial action units' correlation with hypomimia and clinical scores in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Sex Differences in Parkinson's Disease: A Narrative Review.Neurology and therapy · 2025Review
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Authors and funding
49 authors at 20 institutions in 2 countries.
Diego Santos-GarcíaDepartment of Neurology, CHUAC, Complejo Hospitalario Universitario de A Coruña, c/ As Xubias 84, 15006 A Coruña, Spain.ORCID 0000-0002-3126-5111
Ariadna LagunaNeurodegenerative Diseases Research Group, Vall d'Hebron Research Institute (VHIR), 08035 Barcelona, Spain.ORCID 0000-0002-9732-6677
Jorge Hernández-VaraNeurodegenerative Diseases Research Group, Vall d'Hebron Research Institute (VHIR), 08035 Barcelona, Spain.ORCID 0000-0002-9129-5224
Teresa de Deus FonticobaCHUF, Complejo Hospitalario Universitario de Ferrol, 15405 Ferrol, Spain.
Carlos Cores BartoloméDepartment of Neurology, CHUAC, Complejo Hospitalario Universitario de A Coruña, c/ As Xubias 84, 15006 A Coruña, Spain.ORCID 0000-0002-8352-2263
Maria J Feal PainceirasDepartment of Neurology, CHUAC, Complejo Hospitalario Universitario de A Coruña, c/ As Xubias 84, 15006 A Coruña, Spain.
Maria Cristina Íñiguez-AlvaradoDepartment of Neurology, CHUAC, Complejo Hospitalario Universitario de A Coruña, c/ As Xubias 84, 15006 A Coruña, Spain.
Iago García DíazDepartment of Neurology, CHUAC, Complejo Hospitalario Universitario de A Coruña, c/ As Xubias 84, 15006 A Coruña, Spain.ORCID 0000-0003-3304-0714
Silvia JesúsCIBERNED (Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas), 19171 Madrid, Spain.
Maria Teresa BoungiornoHospital Universitari Mutua de Terrassa, 08221 Terrassa, Spain.
Lluís PlanellasClínica del Pilar, 50006 Barcelona, Spain.
Marina CosgayaHospital Clínic de Barcelona, 08036 Barcelona, Spain.
Juan García CaldenteyCentro Neurológico Oms 42, 07003 Palma de Mallorca, Spain.
Nuria CaballolConsorci Sanitari Integral, Hospital Moisés Broggi, 08970 Sant Joan Despí, Spain.
Ines LegardaHospital Universitario Son Espases, 07120 Palma de Mallorca, Spain.
Iria CaboComplejo Hospitalario Universitario de Pontevedra (CHOP), 36001 Pontevedra, Spain.ORCID 0000-0003-2436-6499
Lydia López ManzanaresHospital Universitario La Princesa, 28006 Madrid, Spain.
Isabel González AramburuCIBERNED (Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas), 19171 Madrid, Spain.ORCID 0000-0002-3696-4093
Maria A Ávila RiveraConsorci Sanitari Integral, Hospital General de L'Hospitalet, L'Hospitalet de Llobregat, 08906 Barcelona, Spain.
Víctor Gómez MayordomoHospital Universitario Clínico San Carlos, 28040 Madrid, Spain.ORCID 0000-0001-9343-8439
Víctor NogueiraHospital Da Costa, 27880 Burela, Spain.
Víctor PuenteHospital del Mar, 08003 Barcelona, Spain.
Julio Dotor García-SotoHospital Universitario Virgen Macarena, 41009 Sevilla, Spain.
Carmen BorruéHospital Infanta Sofía, 28702 Madrid, Spain.
Berta Solano VilaInstitut d'Assistència Sanitària (IAS)-Institut Català de la Salut, 17190 Girona, Spain.
María Álvarez SaucoHospital General Universitario de Elche, 03203 Elche, Spain.
Lydia VelaFundación Hospital de Alcorcón, 28922 Madrid, Spain.
Sonia EscalanteHospital de Tortosa Verge de la Cinta (HTVC), 43500 Tortosa, Spain.
Esther CuboComplejo Asistencial Universitario de Burgos, 09006 Burgos, Spain.
Francisco Carrillo PadillaHospital Universitario de Canarias, 38320 San Cristóbal de la Laguna, Spain.
Juan C Martínez CastrilloHospital Universitario Ramón y Cajal, IRYCIS, 28034 Madrid, Spain.ORCID 0000-0001-7744-6850
Pilar Sánchez AlonsoHospital Universitario Puerta de Hierro, 28222 Madrid, Spain.ORCID 0000-0003-0496-4707
Maria G Alonso LosadaHospital Álvaro Cunqueiro, Complejo Hospitalario Universitario de Vigo (CHUVI), 36312 Vigo, Spain.
Nuria López ArizteguiComplejo Hospitalario de Toledo, 45007 Toledo, Spain.ORCID 0000-0001-7172-3191
Itziar GastónComplejo Hospitalario de Navarra, 31008 Pamplona, Spain.
Jaime KulisevskyCIBERNED (Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas), 19171 Madrid, Spain.
Manuel Menéndez GonzálezHospital Universitario Central de Asturias, 33011 Oviedo, Spain.ORCID 0000-0002-5218-0774
Manuel SeijoComplejo Hospitalario Universitario de Pontevedra (CHOP), 36001 Pontevedra, Spain.
Javier Rúiz MartínezHospital Universitario Donostia, 20014 Donostia, Spain.
Caridad ValeroHospital Arnau de Vilanova, 25198 Valencia, Spain.
Mónica KurtisHospital Ruber Internacional, 28034 Madrid, Spain.
Jessica González ArduraHospital de Cabueñes, 33394 Gijón, Spain.
Ruben Alonso RedondoUniversitario Lucus Augusti (HULA), 27003 Lugo, Spain.
Carlos OrdásHospital Rey Juan Carlos, 28933 Madrid, Spain.
Luis M López DíazHospital Álvaro Cunqueiro, Complejo Hospitalario Universitario de Vigo (CHUVI), 36312 Vigo, Spain.
Darrian McAfeeDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Pablo Martinez-MartinCIBERNED (Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas), 19171 Madrid, Spain.ORCID 0000-0003-0837-5280
Pablo MirCIBERNED (Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas), 19171 Madrid, Spain.ORCID 0000-0003-1656-302X
On Behalf Of The Coppadis Study Group
Biomedical Research Networking Center on Neurodegenerative Diseases · ESComplexo Hospitalario Universitario A Coruña · ESComplejo Hospitalario de Pontevedra · ESUniversity Hospital Complex Of Vigo · ESAjuntament de L’Hospitalet · ESComplejo Hospitalario de Navarra · ESComplejo Hospitalario Universitario de Toledo · ESDonostiako Unibertsitate Ospitalea · ESHospital Arnau de Vilanova · ESHospital Clínic de Barcelona · ESHospital Clínico San Carlos · ESHospital Costa del Sol · ESHospital Del Mar · ESHospital de Sant Joan Despí Moisès Broggi · ESHospital de Sant Pau · ESHospital General Universitario de Elche · ESHospital Ruber Internacional · ESHospital Universitari de Tortosa Verge de la Cinta · ESHospital Universitario Central de Asturias · ESHospital Universitario de Burgos · ES
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveSex plays a role in Parkinson's disease (PD) mechanisms. We analyzed sex difference manifestations among Spanish patients with PD. PATIENTS AND
methodsPD patients who were recruited from the Spanish cohort COPPADIS from January 2016 to November 2017 were included. A cross-sectional and a two-year follow-up analysis were conducted. Univariate analyses and general linear model repeated measure were used.
resultsAt baseline, data from 681 PD patients (mean age 62.54 ± 8.93) fit the criteria for analysis. Of them, 410 (60.2%) were males and 271 (39.8%) females. There were no differences between the groups in mean age (62.36 ± 8.73 vs. 62.8 ± 9.24;
conclusionThe present study demonstrates that there are important sex differences in PD. Long-term prospective comparative studies are needed.
Indexed as
gendermotornon-motor symptomsParkinson’s diseasequality of lifesex
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