Evidence map›Paper›PMID 36835823›Full record

ArticleJournal of clinical medicine2023

Heterogeneity of Ocular Hemodynamic Biomarkers among Open Angle Glaucoma Patients of African and European Descent.

Brent Siesky, Alon Harris, Alice Verticchio Vercellin, Julia Arciero, Brendan Fry, George Eckert, Giovanna Guidoboni, Francesco Oddone, Gal Antman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 3 countries.

Brent SieskyDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Alon HarrisDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Alice Verticchio VercellinDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Julia ArcieroDepartment of Mathematical Sciences, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA.
Brendan FryDepartment of Mathematics and Statistics, Metropolitan State University of Denver, Denver, CO 80217, USA.
George EckertDepartment of Biostatistics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.ORCID 0000-0001-7798-7155
Giovanna GuidoboniDepartment of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO 65211, USA.
Francesco OddoneIRCCS Fondazione Bietti, 00198 Rome, Italy.
Gal AntmanDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Icahn School of Medicine at Mount Sinai · USFondazione G.B. Bietti · ITIndiana University – Purdue University Indianapolis · USIndiana University School of MedicineMetropolitan State University of Denver · USRabin Medical Center · ILUniversity of Missouri · US

Funding

Integration of clinical measures and theoretical modeling to quantify sectorial specific changes in ocular structure, function, and hemodynamicsR01EY030851 · NEI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ARCIERO, JULIA, HARRIS, ALON · 2020 to 2023
$1.3M
SCH: SEEthroughGLAUCOMA: Smart Eye Emulator (SEE) to study glaucoma risk factorsR01EY034718 · NEI · UNIVERSITY OF MAINE ORONO · PI GUIDOBONI, GIOVANNA, HARRIS, ALON · 2022 to 2025
$975k
NEI NIH HHS R01 EY030851NEI NIH HHS R01 EY034718
6 · The paper itself

Abstract

This study investigated the heterogeneity of ocular hemodynamic biomarkers in early open angle glaucoma (OAG) patients and healthy controls of African (AD) and European descent (ED). Sixty OAG patients (38 ED, 22 AD) and 65 healthy controls (47 ED, 18 AD) participated in a prospective, cross-sectional study assessing: intraocular pressure (IOP), blood pressure (BP), ocular perfusion pressure (OPP), visual field (VF) and vascular densities (VD) via optical coherence tomography angiography (OCTA). Comparisons between outcomes were adjusted for age, diabetes status and BP. VF, IOP, BP and OPP were not significantly different between OAG subgroups or controls. Multiple VD biomarkers were significantly lower in OAG patients of ED (

Indexed as

African descentAsian descentEuropean descentHispanic descentopen angle glaucomaoptical coherence tomography angiographyrisk factors

Identifiers

PMID36835823
PMCPMC9967448
OpenAlexW4319297689

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.