Evidence map›Paper›PMID 36835819›Full record

ArticleJournal of clinical medicine2023

Artificial Intelligence Based Analysis of Corneal Confocal Microscopy Images for Diagnosing Peripheral Neuropathy: A Binary Classification Model.

Yanda Meng, Frank George Preston, Maryam Ferdousi, Shazli Azmi, Ioannis Nikolaos Petropoulos, Stephen Kaye, Rayaz Ahmed Malik, Uazman Alam, Yalin Zheng

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
8.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  8. Observational
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  14. Painful Diabetic Peripheral Neuropathy: Practical Guidance and Challenges for Clinical Management.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Yanda MengDepartment of Eye and Vision Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK.
Frank George PrestonDepartment of Cardiovascular & Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK.ORCID 0000-0002-3953-331X
Maryam FerdousiInstitute of Cardiovascular Science, University of Manchester, Manchester M13 9PL, UK.
Shazli AzmiInstitute of Cardiovascular Science, University of Manchester, Manchester M13 9PL, UK.
Ioannis Nikolaos PetropoulosDepartment of Medicine, Weill Cornell Medicine-Qatar, Doha 24144, Qatar.
Stephen KayeDepartment of Eye and Vision Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK.ORCID 0000-0003-0390-0592
Rayaz Ahmed MalikDepartment of Medicine, Weill Cornell Medicine-Qatar, Doha 24144, Qatar.ORCID 0000-0002-7188-8903
Uazman AlamDepartment of Cardiovascular & Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK.ORCID 0000-0002-3190-1122
Yalin ZhengDepartment of Eye and Vision Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK.
University of Liverpool · GBUniversity of Manchester · GBWeill Cornell Medical College in Qatar · QA

Funding

Multinational Collaborative Evaluation of Corneal Confocal Microscopy as a Surrogate Endpoint for the Identification and Prediction of Diabetic Neuropathy in Type 1 DiabetesDP3DK104386 · NIDDK · SINAI HEALTH SYSTEM · PI BRIL, VERA, EFRON, NATHAN · 2014 to 2014
$1.1M
Breakthrough T1D 8-2008-362NIDDK NIH HHS DP3 DK104386NIH HHS 1DP3DK104386-01
6 · The paper itself

Abstract

Diabetic peripheral neuropathy (DPN) is the leading cause of neuropathy worldwide resulting in excess morbidity and mortality. We aimed to develop an artificial intelligence deep learning algorithm to classify the presence or absence of peripheral neuropathy (PN) in participants with diabetes or pre-diabetes using corneal confocal microscopy (CCM) images of the sub-basal nerve plexus. A modified ResNet-50 model was trained to perform the binary classification of PN (PN+) versus no PN (PN-) based on the Toronto consensus criteria. A dataset of 279 participants (149 PN-, 130 PN+) was used to train (

Indexed as

artificial intelligencecorneal confocal microscopydiabetic peripheral neuropathy

Identifiers

PMID36835819
PMCPMC9963824
OpenAlexW4319298108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.