Evidence map›Paper›PMID 36835816›Full record

ArticleJournal of clinical medicine2023

Usefulness of Systemic Venous Ultrasound Protocols in the Prognosis of Heart Failure Patients: Results from a Prospective Multicentric Study.

Marta Torres-Arrese, Arantzazu Mata-Martínez, Davide Luordo-Tedesco, Gonzalo García-Casasola, Rodrigo Alonso-González, Esther Montero-Hernández, Marta Cobo-Marcos, Beatriz Sánchez-Sauce, Valentín Cuervas-Mons, Yale Tung-Chen

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Guiding Acute Heart Failure Treatment by Point-of-Care Ultrasound: Validation of a Score Combining Lung Ultrasound and Venous Excess Ultrasound.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Marta Torres-ArreseDepartment of Emergency Medicine, Hospital Universitario Fundación de Alcorcón, Calle Budapest 1, 28922 Alcorcón, Spain.
Arantzazu Mata-MartínezDepartment of Emergency Medicine, Hospital Universitario Fundación de Alcorcón, Calle Budapest 1, 28922 Alcorcón, Spain.
Davide Luordo-TedescoDepartment of Emergency Medicine, Hospital Universitario Infanta Cristina, Avenida 9 de Junio 2, 28981 Parla, Spain.
Gonzalo García-CasasolaDepartment of Emergency Medicine, Hospital Universitario Fundación de Alcorcón, Calle Budapest 1, 28922 Alcorcón, Spain.ORCID 0000-0002-5171-7373
Rodrigo Alonso-GonzálezDepartment of Radiology, Hospital Universitario Severo Ochoa, M-402, s/n, 28914 Leganés, Spain.ORCID 0000-0001-8072-3919
Esther Montero-HernándezDepartment of Internal Medicine, Hospital Universitario Puerta de Hierro-Majadahonda, Centro de Investigación en Red en Enfermedades Cardiovasculares (CIBERCV), Joaquín Rodrigo 1, 28222 Majadahonda, Spain.ORCID 0000-0002-8446-5715
Marta Cobo-MarcosDepartment of Cardiology, Hospital Universitario Puerta de Hierro-Majadahonda, Centro de Investigación en Red en Enfermedades Cardiovasculares (CIBERCV), Joaquín Rodrigo 1, 28222 Majadahonda, Spain.
Beatriz Sánchez-SauceDepartment of Internal Medicine, Hospital Universitario Fundación de Alcorcón, Calle Budapest 1, 28922 Alcorcón, Spain.
Valentín Cuervas-MonsDepartment of Internal Medicine, Hospital Universitario Puerta de Hierro-Majadahonda, Centro de Investigación en Red en Enfermedades Cardiovasculares (CIBERCV), Joaquín Rodrigo 1, 28222 Majadahonda, Spain.
Yale Tung-ChenDepartment of Internal Medicine, Hospital Universitario La Paz, Paseo Castellana 241, 28046 Madrid, Spain.ORCID 0000-0002-5613-3609
Hospital Universitario Fundación Alcorcón · ESCentro de Investigación en Red en Enfermedades Cardiovasculares · ESHospital Universitario Infanta Cristina · ESHospital Universitario La Paz · ESHospital Universitario Severo Ochoa · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mortality and re-admission rates for decompensated acute heart failure (AHF) is increasing overall and risk stratification might be challenging. We sought to evaluate the prognostic role of systemic venous ultrasonography in patients hospitalized for AHF. We prospectively recruited 74 AHF patients with a NT-proBNP level above 500 pg/mL. Then, multi-organ ultrasound assessments (lung, inferior vena cava (IVC), pulsed-wave Doppler (PW-Doppler) of hepatic, portal, intra-renal and femoral veins) were performed at admission, discharge, and follow-up (for 90 days). We also calculated the Venous Excess Ultrasound System (VExUS), a new score of systemic congestion based on IVC dilatation and pulsed-wave Doppler morphology of hepatic, portal and intra-renal veins. An intra-renal monophasic pattern (area under the curve (AUC) 0.923, sensitivity (Sn) 90%, specificity (Sp) 81%, positive predictive value (PPV) 43%, and negative predictive value (NPV) 98%), a portal pulsatility > 50% (AUC 0.749, Sn 80%, Sp 69%, PPV 30%, NPV 96%) and a VExUS score of 3 corresponding to severe congestion (AUC 0.885, Sn 80%, Sp 75%, PPV 33%, and NPV 96%) predicted death during hospitalization. An IVC above 2 cm (AUC 0.758, Sn 93.l% and Sp 58.3) and the presence of an intra-renal monophasic pattern (AUC 0. 834, sensitivity 0.917, specificity 67.4%) in the follow-up visit predicted AHF-related re-admission. Additional scans during hospitalization or the calculation of a VExUS score probably adds unnecessary complexity to the assessment of AHF patients. In conclusion, VExUS score does not contribute to the guidance of therapy or the prediction of complications, compared with the presence of an IVC greater than 2 cm, a venous monophasic intra-renal pattern or a pulsatility > 50% of the portal vein in AHF patients. Early and multidisciplinary follow-up visits remain necessary for the improvement of the prognosis of this highly prevalent disease.

Indexed as

acute heart failureDoppler ultrasoundhepatic veininferior vena cavaintra-renal veinpoint-of-care ultrasoundportal veinvenous excess ultrasonographyVExUS

Identifiers

PMID36835816
PMCPMC9966251
OpenAlexW4319298445

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.