Evidence map›Paper›PMID 36835809›Full record

ReviewJournal of clinical medicine2023

Sepsis-Associated Delirium: A Narrative Review.

Rina Tokuda, Kensuke Nakamura, Yudai Takatani, Chie Tanaka, Yutaka Kondo, Hiroyuki Ohbe, Hiroshi Kamijo, Kosuke Otake, Atsuo Nakamura, Hiroyasu Ishikura and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 50 citations in OpenAlex.

  1. Trial
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  6. Observational
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  9. Transcriptional characterization of sepsis in a LPS porcine model.Molecular genetics and genomics : MGG · 2025
    Article
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  11. Article
  12. Review
  13. Observational
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 1 country.

Rina TokudaTajima Emergency and Critical Care Medical Center, Toyooka Public Hospital, Hyogo 668-8501, Japan.ORCID 0000-0002-9162-0242
Kensuke NakamuraDepartment of Emergency and Critical Care Medicine, Teikyo University Hospital, Tokyo 173-8606, Japan.ORCID 0000-0001-8481-0294
Yudai TakataniDepartment of Primary Care and Emergency Medicine, Kyoto University Hospital, Kyoto 606-8507, Japan.
Chie TanakaDepartment of Emergency and Critical Care Medicine, Nippon Medical School Tama Nagayama Hospital, Tokyo 206-8512, Japan.ORCID 0000-0002-0829-7342
Yutaka KondoDepartment of Emergency and Critical Care Medicine, Juntendo University Urayasu Hospital, Chiba 279-0021, Japan.ORCID 0000-0003-1072-7089
Hiroyuki OhbeDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo 113-8654, Japan.ORCID 0000-0001-8544-2569
Hiroshi KamijoDepartment of Emergency and Critical Care Medicine, Shinshu University Hospital, Nagano 390-0802, Japan.
Kosuke OtakeDepartment of Emergency and Critical Care Center, Nippon Medical School Musashikosugi Hospital, Kanagawa 211-8533, Japan.
Atsuo NakamuraDepartment of Emergency and Critical Care Medicine, Iizuka City Hospital, Fukuoka 820-8505, Japan.
Hiroyasu IshikuraDepartment of Emergency and Critical Care Medicine, Faculty of Medicine, Fukuoka University, Fukuoka 814-0180, Japan.ORCID 0000-0002-4862-5646
Yu KawazoeDepartment of Emergency Critical Care Center, Sendai Medical Center, Miyagi 983-0045, Japan.
J-Stad Japan Sepsis Treatment And Diagnosis Study Group
Nippon Medical School · JPAso Iizuka Hospital · JPFukuoka University · JPJuntendo University Urayasu Hospital · JPKyoto University Hospital · JPSendai Medical Center · JPShinshu University Hospital · JPTeikyo University Hospital · JPThe University of Tokyo · JPToyooka Hospital · JP

Funding

Japan Agency for Medical Research and Development 21fk0108486h0001
6 · The paper itself

Abstract

Delirium is characterized by an acutely altered mental status accompanied by reductions in cognitive function and attention. Delirium in septic patients, termed sepsis-associated delirium (SAD), differs in several specific aspects from the other types of delirium that are typically encountered in intensive care units. Since sepsis and delirium are both closely associated with increased morbidity and mortality, it is important to not only prevent but also promptly diagnose and treat SAD. We herein reviewed the etiology, pathogenesis, risk factors, prevention, diagnosis, treatment, and prognosis of SAD, including coronavirus disease 2019 (COVID-19)-related delirium. Delirium by itself not only worsens long-term prognosis, but it is also regarded as an important factor affecting the outcome of post-intensive care syndrome. In COVID-19 patients, the difficulties associated with adequately implementing the ABCDEF bundle (Assess, prevent, and manage pain; Both spontaneous awakening and breathing trials: Choice of analgesia and sedation; Delirium assess, prevent, and manage; Early mobility and exercise; Family engagement/empowerment) and the need for social isolation are issues that require the development of conventional care for SAD.

Indexed as

COVID-19deliriumpost-intensive care syndromesepsis

Identifiers

PMID36835809
PMCPMC9962483
OpenAlexW4319315756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.