Evidence map›Paper›PMID 36835763›Full record

ReviewInsects2023

Dynamic Roles of Insect Carboxyl/Cholinesterases in Chemical Adaptation.

Casey Cruse, Timothy Walter Moural, Fang Zhu

Open access · goldAbstract readReview
In one paragraph

Review in Insects, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Complex Roles of Insect Cytochrome P450s in Chemical Adaptation.International journal of biological sciences · 2026
    Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Casey CruseDepartment of Entomology, Pennsylvania State University, University Park, State College, PA 16802, USA.
Timothy Walter MouralDepartment of Entomology, Pennsylvania State University, University Park, State College, PA 16802, USA.
Fang ZhuDepartment of Entomology, Pennsylvania State University, University Park, State College, PA 16802, USA.ORCID 0000-0002-6032-2306
Pennsylvania State University · US

Funding

National Science Foundation NSF CAREER IOS-2144082
6 · The paper itself

Abstract

Insects have evolved several intricate defense mechanisms to adapt to their chemical environment. Due to their versatile capabilities in hydrolytic biotransformation, insect carboxyl/cholinesterases (CCEs) play vital roles in the development of pesticide resistance, facilitating the adaptation of insects to their host plants, and manipulating insect behaviors through the olfaction system. CCEs confer insecticide resistance through the mechanisms of qualitative or quantitative changes of CCE-mediated enhanced metabolism or target-site insensitivity, and may contribute to the host plant adaptation. CCEs represent the first odorant-degrading enzymes (ODEs) discovered to degrade insect pheromones and plant odors and remain the most promising ODE candidates. Here, we summarize insect CCE classification, currently characterized insect CCE protein structure characteristics, and the dynamic roles of insect CCEs in chemical adaptation.

Indexed as

catalytic triadhydrolysismetabolic detoxificationodorant-degrading enzymesolfactionpesticide resistancesequestration

Identifiers

PMID36835763
PMCPMC9958613
OpenAlexW4321096775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.