ArticleInternational journal of molecular sciences2023
GPR41 Regulates the Proliferation of BRECs via the PIK3-AKT-mTOR Pathway.
Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Embryonic nano lauric acid delivery modulates lipid metabolism, oxidative balance, and gut morphogenesis in broiler chicks.Scientific reports · 2026Article
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- Dietary L-leucine supplementation improves ruminal fermentation parameters and epithelium development in fattening Angus beef cattle.Journal of animal science and biotechnology · 2025Article
- Role of the Rumen Epithelium and Associated Changes Under High-Concentrate Diets.International journal of molecular sciences · 2025Review
- The characteristics, influence factors, and regulatory strategies of growth retardation in ruminants: a review.Frontiers in veterinary science · 2025Review
- Exploring the effects of Hippo signaling pathway on rumen epithelial proliferation.BMC veterinary research · 2024Article
- Dietary supplementation of sodium butyrate enhances lactation performance by promoting nutrient digestion and mammary gland development in dairy cows.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
- Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Short-chain fatty acids (SCFAs) play a pivotal role in regulating the proliferation and development of bovine rumen epithelial cells (BRECs). G protein-coupled receptor 41 (GPR41) is involved in the signal transduction in BRECs as a receptor for SCFAs. Nevertheless, the impact of GPR41 on the proliferation of BRECs has not been reported. The results of this research showed that the knockdown of GPR41 (GRP41KD) decreased BRECs proliferation compared with the wild-type BRECs (WT) (
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