ReviewInternational journal of molecular sciences2023
Unraveling the Diverse Roles of Neglected Genes Containing Domains of Unknown Function (DUFs): Progress and Perspective.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- The KeyPlants (Basel, Switzerland) · 2026Article
- OsDUF1223 negatively regulates seedling drought tolerance and modulates nitrate-dependent root growth in rice.PLoS genetics · 2026Article
- Article
- Characterization, evolution, and expression profiling of cotton DUF677 protein family and their potential role in drought and salt stress response.BMC plant biology · 2026Article
- Article
- Genome-Wide Analysis of the DUF1664 Family Genes in Peanut (Plants (Basel, Switzerland) · 2026Article
- Identification and Analysis of DUF506 Gene Family in Peanut (Biomolecules · 2026Article
- CysDuF database: annotation and characterization of cysteine residues in domain of unknown function proteins based on cysteine post-translational modifications, their protein microenvironments, biochemical pathways, taxonomy, and diseases.Database : the journal of biological databases and curation · 2026Article
- Tldi1 deficiency mediates Tlde1 self-toxic effect to regulate the adaptability ofFrontiers in cellular and infection microbiology · 2026Article
- Ectopic expression of maize gene ZmDUF1645 in rice affects rice grain traits and cold tolerance.BMC plant biology · 2025Article
- OsSSID6 Negatively Regulates Salt Stress Tolerance in Rice (Oryza Sativa L.) via Metabolic Pathways and ROS Scavenging.Rice (New York, N.Y.) · 2025Article
- cis- and trans-elements for the transcriptional regulation of sugar responsive genes: from current knowledge to future applications.Plant molecular biology · 2025Review
- Do duplication-inducing elements 'cooperate' with genes in evolutionary arms races? A case study on cereal crop pathogenesis.BMC plant biology · 2025Article
- Overexpression of OsDUF846.2 enhances the sensitivity of rice to salt and heat stresses.BMC plant biology · 2025Article
- Methanobrevibacter smithii strain U29 whole genome sequence delineates M. smithii intermediate cell variants.BMC research notes · 2025Article
- Genome-wide identification and characterization of DUF789 genes in cotton: implications for fibre development.BMC plant biology · 2025Article
- Article
- The Case for Limiting "Sequences of Concern" to Those with Demonstrated Pathogenic Function.Applied biosafety : journal of the American Biological Safety Association · 2025Article
- Establishment of enterotype-specific antibodies for various diagnostic systems.Scientific reports · 2025Article
- Identifying Heat Adaptability QTLs and Candidate Genes for Grain Appearance Quality at the Flowering Stage in Rice.Rice (New York, N.Y.) · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Domain of unknown function (DUF) is a general term for many uncharacterized domains with two distinct features: relatively conservative amino acid sequence and unknown function of the domain. In the Pfam 35.0 database, 4795 (24%) gene families belong to the DUF type, yet, their functions remain to be explored. This review summarizes the characteristics of the DUF protein families and their functions in regulating plant growth and development, generating responses to biotic and abiotic stress, and other regulatory roles in plant life. Though very limited information is available about these proteins yet, by taking advantage of emerging omics and bioinformatic tools, functional studies of DUF proteins could be utilized in future molecular studies.
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