Evidence map›Paper›PMID 36835544›Full record

ArticleInternational journal of molecular sciences2023

Intestinal Farnesoid X Receptor Modulates Duodenal Surface Area but Does Not Control Glucose Absorption in Mice.

Jiufang Yang, Theo H van Dijk, Martijn Koehorst, Rick Havinga, Jan Freark de Boer, Folkert Kuipers, Tim van Zutphen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. A novel exopolysaccharide fromGut microbes · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Nuclear Receptors in Health and Diseases.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jiufang YangDepartment of Pediatrics, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.
Theo H van DijkDepartment of Pediatrics, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.
Martijn KoehorstDepartment of Laboratory Medicine, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.
Rick HavingaDepartment of Pediatrics, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.
Jan Freark de BoerDepartment of Pediatrics, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.ORCID 0000-0001-6759-3291
Folkert KuipersDepartment of Pediatrics, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.ORCID 0000-0003-2518-737X
Tim van ZutphenDepartment of Pediatrics, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.
University Medical Center Groningen · NL

Funding

China Scholarship Council 201706350052Netherlands Heart Foundation CVON2018-27
6 · The paper itself

Abstract

Bile acids facilitate the intestinal absorption of dietary lipids and act as signalling molecules in the maintenance of metabolic homeostasis. Farnesoid X receptor (FXR) is a bile acid-responsive nuclear receptor involved in bile acid metabolism, as well as lipid and glucose homeostasis. Several studies have suggested a role of FXR in the control of genes regulating intestinal glucose handling. We applied a novel dual-label glucose kinetic approach in intestine-specific FXR

Indexed as

GlucoseIntestinesAnimalsBile Acids and SaltsIntestinal MucosaMiceMice, Inbred C57BLReceptor, Farnesoid X-ActivatedSignal TransductionBile Acids and SaltsGlucoseReceptor, Farnesoid X-Activatedduodenumglucose absorptionGS3972intestinal FXR

Identifiers

PMID36835544
PMCPMC9961586
OpenAlexW4321374151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.