ArticleInternational journal of molecular sciences2023
Taurine Stimulates AMP-Activated Protein Kinase and Modulates the Skeletal Muscle Functions in Rats via the Induction of Intracellular Calcium Influx.
Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Antibiotic-Mediated Modulation of the Gut Microbiome Identifies Taurine as a Modulator of Adipocyte Function Through TGR5 Signaling.International journal of molecular sciences · 2026Article
- Taurine in canine physiology and metabolic regulation.Frontiers in veterinary science · 2026Review
- Clinical implications of taurine in breast cancer.Biochemistry and biophysics reports · 2025Review
- Article
- Mitigating Effect of Taurine Combined with Corona Dormancy on Oxidative Stress inInternational journal of molecular sciences · 2025Article
- Temperament Upregulates Mitochondrial Enzymes and Negatively Affects Myofibrillar Fragmentation in Beef of ExcitableMetabolites · 2025Article
- Non-targeted LC-MS metabolomics reveals serum metabolites for high-altitude adaptation in Tibetan donkeys.Scientific reports · 2025Article
- Plasma taurine level is linked to symptom burden and clinical outcomes in post-COVID condition.PloS one · 2024Article
- Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Taurine (2-aminoethanesulfonic acid) is a free amino acid abundantly found in mammalian tissues. Taurine plays a role in the maintenance of skeletal muscle functions and is associated with exercise capacity. However, the mechanism underlying taurine function in skeletal muscles has not yet been elucidated. In this study, to investigate the mechanism of taurine function in the skeletal muscles, the effects of short-term administration of a relatively low dose of taurine on the skeletal muscles of Sprague-Dawley rats and the underlying mechanism of taurine function in cultured L6 myotubes were investigated. The results obtained in this study in rats and L6 cells indicate that taurine modulates the skeletal muscle function by stimulating the expression of genes and proteins associated with mitochondrial and respiratory metabolism through the activation of AMP-activated protein kinase via the calcium signaling pathway.
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Registered trials
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