Evidence map›Paper›PMID 36835517›Full record

ReviewInternational journal of molecular sciences2023

Molecularly Imprinted Polymers for the Determination of Cancer Biomarkers.

Greta Pilvenyte, Vilma Ratautaite, Raimonda Boguzaite, Arunas Ramanavicius, Roman Viter, Simonas Ramanavicius

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 91 citations in OpenAlex.

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  20. A Label-Free Photoelectrochemical Biosensor Based on ZnO/CsNanomaterials (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Greta PilvenyteDepartment of Nanotechnology, State Research Institute Center for Physical Sciences and Technology, Saulėtekio Av. 3, LT-10257 Vilnius, Lithuania.ORCID 0000-0002-1895-0130
Vilma RatautaiteDepartment of Nanotechnology, State Research Institute Center for Physical Sciences and Technology, Saulėtekio Av. 3, LT-10257 Vilnius, Lithuania.ORCID 0000-0002-9931-4397
Raimonda BoguzaiteDepartment of Nanotechnology, State Research Institute Center for Physical Sciences and Technology, Saulėtekio Av. 3, LT-10257 Vilnius, Lithuania.ORCID 0000-0002-5178-5907
Arunas RamanaviciusDepartment of Nanotechnology, State Research Institute Center for Physical Sciences and Technology, Saulėtekio Av. 3, LT-10257 Vilnius, Lithuania.ORCID 0000-0002-0885-3556
Roman ViterInstitute of Atomic Physics and Spectroscopy, University of Latvia, 19 Raina Blvd., LV-1586 Riga, Latvia.
Simonas RamanaviciusDepartment of Physical Chemistry, Institute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko Str. 24, LT-03225 Vilnius, Lithuania.ORCID 0000-0003-1432-3866
Vilnius University · LTSumy State University · UA

Funding

EU Horizon 2020 778157 CanBioSe
6 · The paper itself

Abstract

Biomarkers can provide critical information about cancer and many other diseases; therefore, developing analytical systems for recognising biomarkers is an essential direction in bioanalytical chemistry. Recently molecularly imprinted polymers (MIPs) have been applied in analytical systems to determine biomarkers. This article aims to an overview of MIPs used for the detection of cancer biomarkers, namely: prostate cancer (PSA), breast cancer (CA15-3, HER-2), epithelial ovarian cancer (CA-125), hepatocellular carcinoma (AFP), and small molecule cancer biomarkers (5-HIAA and neopterin). These cancer biomarkers may be found in tumours, blood, urine, faeces, or other body fluids or tissues. The determination of low concentrations of biomarkers in these complex matrices is technically challenging. The overviewed studies used MIP-based biosensors to assess natural or artificial samples such as blood, serum, plasma, or urine. Molecular imprinting technology and MIP-based sensor creation principles are outlined. Analytical signal determination methods and the nature and chemical structure of the imprinted polymers are discussed. Based on the reviewed biosensors, the results are compared, and the most suitable materials for each biomarker are discussed.

Indexed as

Biomarkers, TumorBiosensing TechniquesMolecularly Imprinted PolymersNeoplasmsHumansMolecular ImprintingBiomarkers, TumorMolecularly Imprinted Polymersbreast cancer biomarkercancer biomarkerconducting polymer (CP)disease biomarkerselectrochemical sensorepithelial ovarian cancer biomarkerhepatocellular carcinoma biomarkermolecularly imprinted polymer (MIP)prostate cancer biomarkersmall molecule cancer markers

Identifiers

PMID36835517
PMCPMC9961774
OpenAlexW4321377654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.