Evidence map›Paper›PMID 36835421›Full record

ArticleInternational journal of molecular sciences2023

The "ON-OFF" Switching Response of Reactive Oxygen Species in Acute Normobaric Hypoxia: Preliminary Outcome.

Simona Mrakic-Sposta, Maristella Gussoni, Mauro Marzorati, Simone Porcelli, Gerardo Bosco, Costantino Balestra, Michela Montorsi, Claudio Lafortuna, Alessandra Vezzoli

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Simona Mrakic-SpostaInstitute of Clinical Physiology, National Research Council (IFC-CNR), 20162 Milan, Italy.ORCID 0000-0001-7359-2690
Maristella GussoniInstitute of Chemical Sciences and Technologies "G. Natta", National Research Council (SCITEC-CNR), 20133 Milan, Italy.
Mauro MarzoratiInstitute of Biomedical Technologies, National Research Council (ITB-CNR), 20090 Milan, Italy.ORCID 0000-0003-1093-2162
Simone PorcelliDepartment of Molecular Medicine, Università di Pavia, 27100 Pavia, Italy.
Gerardo BoscoDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0001-6595-7944
Costantino BalestraEnvironmental, Occupational, Aging (Integrative) Physiology Laboratory, Haute Ecole Bruxelles-Brabant (HE2B), 1090 Brussels, Belgium.ORCID 0000-0001-6771-839X
Michela MontorsiInstitute of Clinical Physiology, National Research Council (IFC-CNR), 20162 Milan, Italy.ORCID 0000-0001-5152-761X
Claudio LafortunaInstitute of Clinical Physiology, National Research Council (IFC-CNR), 20162 Milan, Italy.ORCID 0000-0002-8625-7653
Alessandra VezzoliInstitute of Clinical Physiology, National Research Council (IFC-CNR), 20162 Milan, Italy.ORCID 0000-0002-0277-163X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to acute normobaric hypoxia (NH) elicits reactive oxygen species (ROS) accumulation, whose production kinetics and oxidative damage were here investigated. Nine subjects were monitored while breathing an NH mixture (0.125 F

Indexed as

AntioxidantsHypoxia8-Hydroxy-2'-DeoxyguanosineAltitudeHumansOxygenReactive Oxygen SpeciesThiobarbituric Acid Reactive Substances8-Hydroxy-2'-DeoxyguanosineAntioxidantsOxygenReactive Oxygen SpeciesThiobarbituric Acid Reactive Substanceselectron paramagnetic resonancenormobaric hypoxiaoxidative stressROSsimulate altitude

Identifiers

PMID36835421
PMCPMC9965553

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.