Evidence map›Paper›PMID 36835383›Full record

ReviewInternational journal of molecular sciences2023

Pathophysiology and Treatment of Chronic Thromboembolic Pulmonary Hypertension.

Naoyuki Otani, Ryo Watanabe, Takashi Tomoe, Shigeru Toyoda, Takanori Yasu, Takaaki Nakamoto

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  14. Pathophysiology and Treatment of Pulmonary Arterial Hypertension.International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Naoyuki OtaniDepartment of Cardiology, Dokkyo Medical University Nikkyo Medical Center, Nikko 321-1298, Japan.
Ryo WatanabeDepartment of Cardiovascular Medicine, Dokkyo Medical University, Mibu 321-0293, Japan.
Takashi TomoeDepartment of Cardiology, Dokkyo Medical University Nikkyo Medical Center, Nikko 321-1298, Japan.
Shigeru ToyodaDepartment of Cardiovascular Medicine, Dokkyo Medical University, Mibu 321-0293, Japan.ORCID 0000-0002-8260-833X
Takanori YasuDepartment of Cardiology, Dokkyo Medical University Nikkyo Medical Center, Nikko 321-1298, Japan.ORCID 0000-0002-1940-2347
Takaaki NakamotoDepartment of Cardiology, Dokkyo Medical University Nikkyo Medical Center, Nikko 321-1298, Japan.
Dokkyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) is a condition in which an organic thrombus remains in the pulmonary artery (PA) even after receiving anticoagulation therapy for more than 3 months and is complicated by pulmonary hypertension (PH), leading to right-sided heart failure and death. CTEPH is a progressive pulmonary vascular disease with a poor prognosis if left untreated. The standard treatment for CTEPH is pulmonary endarterectomy (PEA), which is usually performed only in specialized centers. In recent years, balloon pulmonary angioplasty (BPA) and drug therapy for CTEPH have also shown good results. This review discusses the complex pathogenesis of CTEPH and presents the standard of care, PEA, as well as a new device called BPA, which is showing remarkable progress in efficacy and safety. Additionally, several drugs are now demonstrating established evidence of efficacy in treating CTEPH.

Indexed as

Angioplasty, BalloonHypertension, PulmonaryPulmonary EmbolismChronic DiseaseHumansPulmonary Arteryballoon pulmonary angioplastychronic thromboembolic pulmonary hypertensionpulmonary endarterectomy

Identifiers

PMID36835383
PMCPMC9968103
OpenAlexW4321103757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.