Evidence map›Paper›PMID 36835339›Full record

ReviewInternational journal of molecular sciences2023

Impact of Microplastics on the Ocular Surface.

Duoduo Wu, Blanche X H Lim, Ivan Seah, Shay Xie, Julia E Jaeger, Robert K Symons, Amy L Heffernan, Emily E M Curren, Sandric C Y Leong, Andri K Riau and 8 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Plastics in dermatology: A review and solutions.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 3 countries.

Duoduo WuDepartment of Ophthalmology, National University Health System, Singapore 119228, Singapore.ORCID 0000-0002-2247-0949
Blanche X H LimDepartment of Ophthalmology, National University Health System, Singapore 119228, Singapore.
Ivan SeahDepartment of Ophthalmology, National University Health System, Singapore 119228, Singapore.ORCID 0000-0001-7843-1917
Shay XieEurofins Environment Testing Australia & New Zealand, Dandenong, VIC 3175, Australia.
Julia E JaegerEurofins Environment Testing Australia & New Zealand, Dandenong, VIC 3175, Australia.
Robert K SymonsEurofins Environment Testing Australia & New Zealand, Dandenong, VIC 3175, Australia.ORCID 0000-0002-6624-3553
Amy L HeffernanEurofins Environment Testing Australia & New Zealand, Dandenong, VIC 3175, Australia.
Emily E M CurrenSt. John's Island National Marine Laboratory, Tropical Marine Science Institute, National University of Singapore, Singapore 119077, Singapore.
Sandric C Y LeongSt. John's Island National Marine Laboratory, Tropical Marine Science Institute, National University of Singapore, Singapore 119077, Singapore.ORCID 0000-0002-6767-0020
Andri K RiauSingapore Eye Research Institute, Singapore 169856, Singapore.ORCID 0000-0002-5105-0484
Dawn K A LimDepartment of Ophthalmology, National University Health System, Singapore 119228, Singapore.
Fiona StapletonSchool of Optometry and Vision Science, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-7203-5443
Mohammad Javed AliLV Prasad Eye Institute, Hyderabad 500034, India.ORCID 0000-0002-6363-9202
Swati SinghLV Prasad Eye Institute, Hyderabad 500034, India.
Louis TongSingapore Eye Research Institute, Singapore 169856, Singapore.
Jodhbir S MehtaSingapore Eye Research Institute, Singapore 169856, Singapore.ORCID 0000-0001-6362-4898
Xinyi SuDepartment of Ophthalmology, National University Health System, Singapore 119228, Singapore.
Chris H L LimDepartment of Ophthalmology, National University Health System, Singapore 119228, Singapore.ORCID 0000-0003-2219-3184
National University of Singapore · SGL V Prasad Eye Institute · INSingapore National Eye Center · SGNational University Health System · SGSingapore Eye Research Institute · SGUNSW Sydney · AU

Funding

Singhealth Medical Student Talent Development Award NA
6 · The paper itself

Abstract

Plastics are synthetic materials made from organic polymers that are ubiquitous in daily living and are especially important in the healthcare setting. However, recent advances have revealed the pervasive nature of microplastics, which are formed by degradation of existing plastic products. Although the impact on human health has yet to be fully characterised, there is increasing evidence that microplastics can trigger inflammatory damage, microbial dysbiosis, and oxidative stress in humans. Although there are limited studies investigating their effect on the ocular surface, studies of microplastics on other organs provide some insights. The prevalence of plastic waste has also triggered public outcry, culminating in the development of legislation aimed at reducing microplastics in commercial products. We present a review outlining the possible sources of microplastics leading to ocular exposure, and analyse the possible mechanisms of ocular surface damage. Finally, we examine the utility and consequences of current legislation surrounding microplastic regulation.

Indexed as

MicroplasticsWater Pollutants, ChemicalEnvironmental MonitoringHumansPlasticsMicroplasticsPlasticsWater Pollutants, Chemicaldry eye diseasedysbiosisinflammationmicroplasticsocular surfaceoxidative stresspolymers

Identifiers

PMID36835339
PMCPMC9962686
OpenAlexW4321001961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.