Evidence map›Paper›PMID 36835338›Full record

ArticleInternational journal of molecular sciences2023

Mechanisms for the α-Adrenoceptor-Mediated Positive Inotropy in Mouse Ventricular Myocardium: Enhancing Effect of Action Potential Prolongation.

Shogo Hamaguchi, Ikue Morinou, Yuko Shiseki, Ayako Mikami, Maika Seki, Iyuki Namekata, Hikaru Tanaka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Molecular Mechanisms of Cardiac Development and Disease.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shogo HamaguchiDepartment of Pharmacology, Faculty of Pharmacological Science, Toho University, Chiba 274-8510, Japan.
Ikue MorinouDepartment of Pharmacology, Faculty of Pharmacological Science, Toho University, Chiba 274-8510, Japan.
Yuko ShisekiDepartment of Pharmacology, Faculty of Pharmacological Science, Toho University, Chiba 274-8510, Japan.
Ayako MikamiDepartment of Pharmacology, Faculty of Pharmacological Science, Toho University, Chiba 274-8510, Japan.
Maika SekiDepartment of Pharmacology, Faculty of Pharmacological Science, Toho University, Chiba 274-8510, Japan.
Iyuki NamekataDepartment of Pharmacology, Faculty of Pharmacological Science, Toho University, Chiba 274-8510, Japan.
Hikaru TanakaDepartment of Pharmacology, Faculty of Pharmacological Science, Toho University, Chiba 274-8510, Japan.
Toho University · JP

Funding

Japan Society for the Promotion of Science JP20K07091Japan Society for the Promotion of Science JP20K07299Japan Society for the Promotion of Science JP20K16013
6 · The paper itself

Abstract

Mechanisms for the α-adrenoceptor-mediated positive inotropy in neonatal mouse ventricular myocardium were studied with isolated myocardial preparations. The phenylephrine-induced positive inotropy was suppressed by prazosin, nifedipine, and chelerythrine, a protein kinase C inhibitor, but not by SEA0400, a selective Na

Indexed as

Myocardial ContractionMyocardiumAction PotentialsAnimalsCromakalimMicePhenylephrineReceptors, AdrenergicCromakalimPhenylephrineReceptors, Adrenergicaction potential durationL-type Ca2+ channelmouse ventricleα-adrenergic receptor

Identifiers

PMID36835338
PMCPMC9964142
OpenAlexW4320918259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.