Evidence map›Paper›PMID 36835325›Full record

ReviewInternational journal of molecular sciences2023

DNA Damage and Repair in Eye Diseases.

Joanna Sohn, Sang-Eun Lee, Eun-Yong Shim

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Epigenetics in Glaucoma.Medicina (Kaunas, Lithuania) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joanna SohnDepartment of Molecular Medicine, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Sang-Eun LeeDepartment of Molecular Medicine, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.ORCID 0000-0002-0799-4701
Eun-Yong ShimDepartment of Molecular Medicine, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
The University of Texas Health Science Center at San Antonio · US

Funding

REPAIR OF DNA ENDS WITH ADDUCTSR01GM141631 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SANG EUN LEE · 2023 to 2026
$1.4M
Role of RTEL1 in Microhomology-Mediated End JoiningR21ES031772 · NIEHS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI DALEY, JAMES MATTHEW, LEE, SANG EUN · 2021 to 2022
$425k
NIEHS NIH HHS R21 ES031772NIGMS NIH HHS R01 GM141631
6 · The paper itself

Abstract

Vision is vital for daily activities, and yet the most common eye diseases-cataracts, DR, ARMD, and glaucoma-lead to blindness in aging eyes. Cataract surgery is one of the most frequently performed surgeries, and the outcome is typically excellent if there is no concomitant pathology present in the visual pathway. In contrast, patients with DR, ARMD and glaucoma often develop significant visual impairment. These often-multifactorial eye problems can have genetic and hereditary components, with recent data supporting the role of DNA damage and repair as significant pathogenic factors. In this article, we discuss the role of DNA damage and the repair deficit in the development of DR, ARMD and glaucoma.

Indexed as

CataractEye DiseasesGlaucomaMacular DegenerationBlindnessDNA DamageHumansage-related macular degenerationdiabetic retinopathyDNA damage and repairglaucoma

Identifiers

PMID36835325
PMCPMC9964121
OpenAlexW4320918571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.