Evidence map›Paper›PMID 36835188›Full record

ArticleInternational journal of molecular sciences2023

Survey of Protein Sequence Embedding Models.

Chau Tran, Siddharth Khadkikar, Aleksey Porollo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

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  6. Computational function prediction of bacteria and phage proteins.Microbiology and molecular biology reviews : MMBR · 2025
    Review
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  15. Progress of the "Molecular Informatics" Section in 2022.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Chau TranDepartment of Computer Science, University of Cincinnati, Cincinnati, OH 45219, USA.
Siddharth KhadkikarDepartment of Computer and Data Sciences, Case Western Reserve University, Cleveland, OH 44106, USA.
Aleksey PorolloCenter for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.ORCID 0000-0002-3202-5099
Case Western Reserve University · USCincinnati Children's Hospital Medical Center · USUniversity of Cincinnati · US

Funding

Copper tolerance and homeostasis in Pneumocystis speciesR21AI143467 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI POROLLO, ALEXEY · 2019 to 2020
$454k
NIAID NIH HHS R21 AI143467NIH HHS R21-AI143467
6 · The paper itself

Abstract

Derived from the natural language processing (NLP) algorithms, protein language models enable the encoding of protein sequences, which are widely diverse in length and amino acid composition, in fixed-size numerical vectors (embeddings). We surveyed representative embedding models such as Esm, Esm1b, ProtT5, and SeqVec, along with their derivatives (GoPredSim and PLAST), to conduct the following tasks in computational biology: embedding the

Indexed as

AlgorithmsProteinsAmino AcidsAmino Acid SequenceComputational BiologyHumansProteomicsSaccharomyces cerevisiaeAmino AcidsProteinsdeep learningnatural language processingprotein annotationprotein language modelprotein sequence embeddingsurvey of embedding models

Identifiers

PMID36835188
PMCPMC9963412
OpenAlexW4320731502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.