Evidence map›Paper›PMID 36835169›Full record

ArticleInternational journal of molecular sciences2023

Bio-Guided Isolation of Compounds from

Małgorzata Kołtun-Jasion, Paulina Sawulska, Andrzej Patyra, Marta Woźniak, Marta Katarzyna Dudek, Agnieszka Filipek, Anna Karolina Kiss

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Małgorzata Kołtun-JasionDepartment of Pharmaceutical Biology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0001-9501-5325
Paulina SawulskaDepartment of Pharmaceutical Biology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
Andrzej PatyraDepartment of Pharmaceutical Biology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0003-4981-6660
Marta WoźniakDepartment of Pharmaceutical Biology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
Marta Katarzyna DudekStructural Studies Department, Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza H. 112, 90-001 Łódź, Poland.ORCID 0000-0003-3412-0177
Agnieszka FilipekDepartment of Pharmaceutical Biology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0002-1351-3687
Anna Karolina KissDepartment of Pharmaceutical Biology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
Medical University of Warsaw · PLCentrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk · PLÉcole Nationale Supérieure de Chimie de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is the first physiological defence mechanism against external and internal stimuli. The prolonged or inappropriate response of the immune system may lead to the persistent inflammatory response that can potentially become a basis for chronic diseases e.g., asthma, type II diabetes or cancer. An important role in the alleviation of inflammatory processes, as an adjunct to traditional pharmacological therapy, is attributed to phytotherapy, especially to raw materials with a long tradition of use, e.g., ash leaves. Despite their long-term use in phytotherapy, the specific mechanisms of action have not been confirmed in a sufficient number of biological or clinical studies. The aim of the study is a detailed phytochemical analysis of infusion and its fractions, isolation of pure compounds from the leaves of

Indexed as

Anti-Inflammatory AgentsFraxinusPhytochemicalsCytokinesDiabetes Mellitus, Type 2GlucosidesGlycosidesHumansInterleukin-6Leukocytes, MononuclearLipopolysaccharidesMacrophagesPlant ExtractsPyransTandem Mass SpectrometryTriterpenesAnti-Inflammatory AgentsCytokinesformosideGlucosidesGlycosidesInterleukin-6ligstrosideLipopolysaccharidesoleoacteosidePhytochemicalsPlant ExtractsPyransTriterpenesTumor Necrosis Factor-alphaash leavescytokinesflavonoidsFraxinus excelsiorIL-10 receptorinflammationmacrophagesmonocytesOleaceaephenylethanoidssecoiridoids

Identifiers

PMID36835169
PMCPMC9964138
OpenAlexW4320731256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.