Evidence map›Paper›PMID 36835098›Full record

ReviewInternational journal of molecular sciences2023

Disassembly of Amyloid Fibril with Infrared Free Electron Laser.

Takayasu Kawasaki, Koichi Tsukiyama, Phuong H Nguyen

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Takayasu KawasakiAccelerator Laboratory, High Energy Accelerator Research Organization, 1-1 Oho, Tsukuba 305-0801, Japan.ORCID 0000-0001-8376-5807
Koichi TsukiyamaDepartment of Chemistry, Faculty of Science Division I, Tokyo University of Science, 1-3 Kagurazaka, Tokyo 184-8501, Japan.
Phuong H NguyenCNRS, UPR 9080, Laboratoire de Biochimie Théorique, Institut de Biologie Physico-Chimique, Fondation Edmond de Rothschild, Université Paris Cité, 13 Rue Pierre et Marie Curie, 75005 Paris, France.
Centre National de la Recherche Scientifique · FRHigh Energy Accelerator Research Organization · JPTokyo University of Science · JP

Funding

Japan Society for the Promotion of Science JP20K12483
6 · The paper itself

Abstract

Amyloid fibril causes serious amyloidosis such as neurodegenerative diseases. The structure is composed of rigid β-sheet stacking conformation which makes it hard to disassemble the fibril state without denaturants. Infrared free electron laser (IR-FEL) is an intense picosecond pulsed laser that is oscillated through a linear accelerator, and the oscillation wavelengths are tunable from 3 μm to 100 μm. Many biological and organic compounds can be structurally altered by the mode-selective vibrational excitations due to the wavelength variability and the high-power oscillation energy (10-50 mJ/cm

Indexed as

AmyloidElectronsAmidesLasersPeptidesAmidesAmyloidPeptidesamide Iamyloid fibrildisassemblyinfrared free electron laservibrational excitationα-helixβ-sheet

Identifiers

PMID36835098
PMCPMC9967569
OpenAlexW4320492941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.