Evidence map›Paper›PMID 36835078›Full record

ArticleInternational journal of molecular sciences2023

Increased Density of Endogenous Adenosine A

Héctor Godoy-Marín, Verónica Jiménez-Sábado, Carmen Tarifa, Antonino Ginel, Joana Larupa Dos Santos, Bo Hjorth Bentzen, Leif Hove-Madsen, Francisco Ciruela

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Therapeutic advances in atrial fibrillation based on animal models.Journal of Zhejiang University. Science. B · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Héctor Godoy-MarínPharmacology Unit, Department of Pathology and Experimental Therapeutics, School of Medicine and Health Sciences, Institute of Neurosciences, University of Barcelona, 08907 L'Hospitalet de Llobregat, Spain.
Verónica Jiménez-SábadoBiomedical Research Institute Sant Pau, IIB Sant Pau, 08025 Barcelona, Spain.ORCID 0000-0001-7720-988X
Carmen TarifaBiomedical Research Institute Sant Pau, IIB Sant Pau, 08025 Barcelona, Spain.
Antonino GinelDepartment Cardiac Surgery, Hospital de la Santa Creu i Sant Pau, 08036 Barcelona, Spain.ORCID 0000-0002-8820-7545
Joana Larupa Dos SantosDepartment of Biomedical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.ORCID 0000-0002-0690-7741
Bo Hjorth BentzenDepartment of Biomedical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.
Leif Hove-MadsenBiomedical Research Institute Sant Pau, IIB Sant Pau, 08025 Barcelona, Spain.ORCID 0000-0001-5493-3998
Francisco CiruelaPharmacology Unit, Department of Pathology and Experimental Therapeutics, School of Medicine and Health Sciences, Institute of Neurosciences, University of Barcelona, 08907 L'Hospitalet de Llobregat, Spain.ORCID 0000-0003-0832-3739
Bellvitge University Hospital · ESCentro de Investigación Biomédica en Red · ESUniversity of Copenhagen · DKHospital de Sant Pau · ESInstitut d'Investigacions Biomèdiques de Barcelona · ES

Funding

Fundació La Marató TV3 Grant 20152030/31Ministerio de Ciencia, Innovación y Universidades PID2020-116927RB-C21Ministerio de Ciencia, Innovación y Universidades PID2020-118511RB-I00
6 · The paper itself

Abstract

Adenosine, an endogenous nucleoside, plays a critical role in maintaining homeostasis during stressful situations, such as energy deprivation or cellular damage. Therefore, extracellular adenosine is generated locally in tissues under conditions such as hypoxia, ischemia, or inflammation. In fact, plasma levels of adenosine in patients with atrial fibrillation (AF) are elevated, which also correlates with an increased density of adenosine A

Indexed as

Atrial FibrillationReceptor, Adenosine A2AAdenosineAnimalsHeart AtriaHumansLeukocytes, MononuclearMyocytes, CardiacSwineAdenosineReceptor, Adenosine A2AA2AR densityadenosine A2AR receptorAF patientsatrial fibrillationHL-1 cellstachypaced pig

Identifiers

PMID36835078
PMCPMC9963500
OpenAlexW4320493188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.