Evidence map›Paper›PMID 36835067›Full record

ArticleInternational journal of molecular sciences2023

Osteoblasts and Fibroblasts Interaction with a Porcine Acellular Dermal Matrix Membrane.

Pietro Felice, Emira D'Amico, Tania Vanessa Pierfelice, Morena Petrini, Carlo Barausse, Maryia Karaban, Antonio Barone, Giovanna Iezzi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Pietro FeliceDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.
Emira D'AmicoDepartment of Medical, Oral and Biotechnological Sciences, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0003-2414-7130
Tania Vanessa PierfeliceDepartment of Medical, Oral and Biotechnological Sciences, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-5886-2186
Morena PetriniDepartment of Medical, Oral and Biotechnological Sciences, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-3849-4304
Carlo BarausseDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.
Maryia KarabanDepartment of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy.
Antonio BaroneUnit of Oral Surgery and Implantology, University Hospitals of Geneva, University of Geneva, 1205 Geneva, Switzerland.
Giovanna IezziDepartment of Medical, Oral and Biotechnological Sciences, University G. d'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.
University of Chieti-Pescara · ITUniversity of Bologna · ITUniversity of Modena and Reggio Emilia · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of collagen membranes has remained the gold standard in GTR/GBR. In this study, the features and the biological activities of an acellular porcine dermis collagen matrix membrane applicable during dental surgery were investigated, and also by applying hydration with NaCl. Thus, two tested membranes were distinguished, the H-Membrane and Membrane, compared to the control cell culture plastic. The characterization was performed by SEM and histological analyses. In contrast, the biocompatibility was investigated on HGF and HOB cells at 3, 7, and 14 days by MTT for proliferation study; by SEM and histology for cell interaction study; and by RT-PCR for function-related genes study. In HOBs seeded on membranes, mineralization functions by ALP assay and Alizarin Red staining were also investigated. Results indicated that the tested membranes, especially when hydrated, can promote the proliferation and attachment of cells at each time. Furthermore, membranes significantly increased ALP and mineralization activities in HOBs as well as the osteoblastic-related genes

Indexed as

Acellular DermisCell Culture TechniquesAnimalsCollagenFibroblastsOsteoblastsSwineCollagenALPCOL1collagendermal matrix membraneFN1human gingival fibroblastshuman oral osteoblastsMMP8OCN

Identifiers

PMID36835067
PMCPMC9964429
OpenAlexW4320496551

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.