Evidence map›Paper›PMID 36835017›Full record

ArticleInternational journal of molecular sciences2023

Altered Faecal Microbiota Composition and Structure of Ghanaian Children with Acute Gastroenteritis.

Emmanuel Kofi Quaye, Raymond Lovelace Adjei, Abiola Isawumi, David J Allen, J Gregory Caporaso, Osbourne Quaye

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. A One-Health Perspective onEnvironmental health insights · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Emmanuel Kofi QuayeWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra P.O. Box LG 54, Ghana.
Raymond Lovelace AdjeiCouncil for Scientific and Industrial Research (CSIR)-Animal Research Institute, Accra P.O. Box AH 20, Ghana.
Abiola IsawumiWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra P.O. Box LG 54, Ghana.ORCID 0000-0003-2141-2509
David J AllenDepartment of Infection Biology, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.ORCID 0000-0002-1194-0415
J Gregory CaporasoCentre for Applied Microbiome Science, Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011, USA.ORCID 0000-0002-8865-1670
Osbourne QuayeWest African Centre for Cell Biology of Infectious Pathogens (WACCBIP), Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra P.O. Box LG 54, Ghana.ORCID 0000-0002-0621-876X
University of Ghana · GHCouncil for Scientific and Industrial Research · GHLondon School of Hygiene & Tropical Medicine · GBNorthern Arizona University · US

Funding

Wellcome Trust DEL-15-007: Awandare
6 · The paper itself

Abstract

Acute gastroenteritis (AGE) is a disease of global public health importance. Recent studies show that children with AGE have an altered gut microbiota relative to non-AGE controls. Yet, how the gut microbiota differs in Ghanaian children with and without AGE remains unclear. Here, we explore the 16S rRNA gene-based faecal microbiota profiles of Ghanaian children five years of age and younger, comprising 57 AGE cases and 50 healthy controls. We found that AGE cases were associated with lower microbial diversity and altered microbial sequence profiles relative to the controls. The faecal microbiota of AGE cases was enriched for disease-associated bacterial genera, including

Indexed as

GastroenteritisMicrobiotaBacteriaChildFecesGhanaHumansRNA, Ribosomal, 16SRNA, Ribosomal, 16Sacute gastroenteritisbacteriachildrencorrelation networkdiseasefaecal microbiotapathogen

Identifiers

PMID36835017
PMCPMC9962333
OpenAlexW4320493720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.