ArticleInternational journal of molecular sciences2023
An Experimental Anodized and Low-Pressure Oxygen Plasma-Treated Titanium Dental Implant Surface-Preliminary Report.
Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- RANKL, OPG, and CTS-K Release in Bone Response to Immediate Nonfunctional Loading of a Single Implant in Mandibular Molar Sites During Osseointegration Establishment.Clinical and experimental dental research · 2025Trial
- Surface Modifications of cpTi and Ti-6Al‑4V: The Synergistic Potential of PEO-CaP for Optimized Dental Implant Performance.ACS omega · 2026Article
- Research Progress and Translational Perspectives of Piezoelectric Materials in Dental Implant Surface Engineering.Journal of functional biomaterials · 2026Review
- Bone Regeneration After Maxillary Sinus Augmentation with Allogeneic and Xenogeneic Biomaterials with Adjunctive Photobiomodulation: Histological and Radiological Secondary Outcomes of a Randomized Clinical Trial.Journal of functional biomaterials · 2026Article
- Microporous zirconium-coated titanium surfaces for dental implant application: Surface characterization, bioactivity and effect on the oral biofilm formation.Journal of materials science. Materials in medicine · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Chemical composition and physical parameters of the implant surface, such as roughness, regulate the cellular response leading to implant bone osseointegration. Possible implant surface modifications include anodization or the plasma electrolytic oxidation (PEO) treatment process that produces a thick and dense oxide coating superior to normal anodic oxidation. Experimental modifications with Plasma Electrolytic Oxidation (PEO) titanium and titanium alloy Ti6Al4V plates and PEO additionally treated with low-pressure oxygen plasma (PEO-S) were used in this study to evaluate their physical and chemical properties. Cytotoxicity of experimental titanium samples as well as cell adhesion to their surface were assessed using normal human dermal fibroblasts (NHDF) or L929 cell line. Moreover, the surface roughness, fractal dimension analysis, and texture analysis were calculated. Samples after surface treatment have substantially improved properties compared to the reference SLA (sandblasted and acid-etched) surface. The surface roughness (Sa) was 0.59-2.38 µm, and none of the tested surfaces had cytotoxic effect on NHDF and L929 cell lines. A greater cell growth of NHDF was observed on the tested PEO and PEO-S samples compared to reference SLA sample titanium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.