Evidence map›Paper›PMID 36834987›Full record

ArticleInternational journal of molecular sciences2023

Expression of Epithelial and Mesenchymal Markers in Plasmatic Extracellular Vesicles as a Diagnostic Tool for Neoplastic Processes.

Begoña O Alen, Lara Sofía Estévez-Pérez, María Otero Alén, Saioa Domínguez Hormaetxe, Laureano Simón, Ángel Concha

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. [Molecular imprinting strategies and advances targeting biomembranes].Se pu = Chinese journal of chromatography · 2026
    Review
  3. Unraveling the metastatic niche in breast cancer bone metastasis through single-cell RNA sequencing.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Begoña O AlenMolecular Biology Area, Department of Anatomical Pathology, Biomedical Research Institute A Coruña (INIBIC), University Hospital Complex A Coruña, 15006 A Coruña, Spain.ORCID 0000-0002-2876-6732
Lara Sofía Estévez-PérezMolecular Biology Area, Department of Anatomical Pathology, Biomedical Research Institute A Coruña (INIBIC), University Hospital Complex A Coruña, 15006 A Coruña, Spain.
María Otero AlénSantiago de Compostela Health Research Institute (IDIS), University Hospital Complex Santiago de Compostela, 15706 Santiago de Compostela, Spain.
Saioa Domínguez HormaetxeOncomatryx Biopharma, 48160 Derio, Spain.
Laureano SimónOncomatryx Biopharma, 48160 Derio, Spain.
Ángel ConchaMolecular Biology Area, Department of Anatomical Pathology, Biomedical Research Institute A Coruña (INIBIC), University Hospital Complex A Coruña, 15006 A Coruña, Spain.
Instituto de Investigación Biomédica de A Coruña · ESOncomatryx (Spain) · ESInstituto de Investigación Sanitaria de Santiago · ES

Funding

Fundación Profesor Novoa Santos grant Fundación Profesor Novoa Santos grantServizo Galego de Saúde AB-SER1-19-008 L3
6 · The paper itself

Abstract

Tumor-derived extracellular vesicles (TD-EVs) have active roles as cancer hallmark enablers. EVs RNA of epithelial and stromal cells carry information that facilitates the communication processes that contribute to oncological progression, so the objective of this work was to validate by RT-PCR the presence of epithelial (

Indexed as

Biomarkers, TumorEpithelial-Mesenchymal TransitionExtracellular VesiclesCollagen Type IExosomesHumansNeoplastic ProcessesRNABiomarkers, TumorCollagen Type ICollagen Type I, alpha2 SubunitRNAcancer diagnosisepithelial biomarkerextracellular vesiclesliquid biopsymesenchymal biomarker

Identifiers

PMID36834987
PMCPMC9964693
OpenAlexW4319970849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.