Evidence map›Paper›PMID 36834827›Full record

ArticleInternational journal of molecular sciences2023

Hyperoxidized Species of Heme Have a Potent Capacity to Induce Autoreactivity of Human IgG Antibodies.

Marie Wiatr, Maya Hadzhieva, Maxime Lecerf, Rémi Noé, Sune Justesen, Sébastien Lacroix-Desmazes, Marie-Agnès Dragon-Durey, Jordan D Dimitrov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Marie WiatrCentre de Recherche des Cordeliers, INSERM, CNRS, Sorbonne Université, Université Paris Cité, 75006 Paris, France.
Maya HadzhievaCentre de Recherche des Cordeliers, INSERM, CNRS, Sorbonne Université, Université Paris Cité, 75006 Paris, France.
Maxime LecerfCentre de Recherche des Cordeliers, INSERM, CNRS, Sorbonne Université, Université Paris Cité, 75006 Paris, France.
Rémi NoéCentre de Recherche des Cordeliers, INSERM, CNRS, Sorbonne Université, Université Paris Cité, 75006 Paris, France.ORCID 0000-0003-3474-4035
Sune JustesenImmunitrack Aps, Lersoe Park Alle 42, 2100 Copenhagen, Denmark.
Sébastien Lacroix-DesmazesCentre de Recherche des Cordeliers, INSERM, CNRS, Sorbonne Université, Université Paris Cité, 75006 Paris, France.
Marie-Agnès Dragon-DureyCentre de Recherche des Cordeliers, INSERM, CNRS, Sorbonne Université, Université Paris Cité, 75006 Paris, France.
Jordan D DimitrovCentre de Recherche des Cordeliers, INSERM, CNRS, Sorbonne Université, Université Paris Cité, 75006 Paris, France.
Centre National de la Recherche Scientifique · FR

Funding

Agence Nationale de la Recherche ANR-13-JCV1-006-01European Research Council ERC-StG-678905
6 · The paper itself

Abstract

The interaction of some human antibodies with heme results in posttranslational acquisition of binding to various self- and pathogen-derived antigens. The previous studies on this phenomenon were performed with oxidized heme (Fe

Indexed as

HemeImmunoglobulin GAdaptive ImmunityHumansInfant, NewbornIronOxidation-ReductionHemeImmunoglobulin GIronantibodiesautoreactivityhemeoxidative modificationspolyreactivity

Identifiers

PMID36834827
PMCPMC9960230
OpenAlexW4319762279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.