Evidence map›Paper›PMID 36834821›Full record

ReviewInternational journal of molecular sciences2023

Adverse Human Health Effects of Chromium by Exposure Route: A Comprehensive Review Based on Toxicogenomic Approach.

Dong Yeop Shin, Sang Min Lee, Yujin Jang, Jun Lee, Cheol Min Lee, Eun-Min Cho, Young Rok Seo

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
22.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Boron-Doped Carbon Dots Derived From Herbal Mixture for Selective Fluorimetric Sensing of CrLuminescence : the journal of biological and chemical luminescence · 2026
    Article
  6. Oyster Mushroom Cultivation on Coffee Parchment andJournal of fungi (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. The Comparison of Fresh and Dry Duckweed (Plants (Basel, Switzerland) · 2026
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dong Yeop ShinInstitute of Environmental Medicine for Green Chemistry, Department of Life Science, Dongguk University Biomedi Campus, 32 Dongguk-ro, Ilsandong-gu, Goyang-si 10326, Republic of Korea.
Sang Min LeeInsilicogen Inc., Suwon 441813, Republic of Korea.
Yujin JangInstitute of Environmental Medicine for Green Chemistry, Department of Life Science, Dongguk University Biomedi Campus, 32 Dongguk-ro, Ilsandong-gu, Goyang-si 10326, Republic of Korea.
Jun LeeInstitute of Environmental Medicine for Green Chemistry, Department of Life Science, Dongguk University Biomedi Campus, 32 Dongguk-ro, Ilsandong-gu, Goyang-si 10326, Republic of Korea.
Cheol Min LeeDepartment of Nano, Chemical & Biological Engineering, College of Natural Science and Engineering, Seokyeong University, Seoul 02173, Republic of Korea.ORCID 0000-0003-2276-2463
Eun-Min ChoDepartment of Nano, Chemical & Biological Engineering, College of Natural Science and Engineering, Seokyeong University, Seoul 02173, Republic of Korea.
Young Rok SeoInstitute of Environmental Medicine for Green Chemistry, Department of Life Science, Dongguk University Biomedi Campus, 32 Dongguk-ro, Ilsandong-gu, Goyang-si 10326, Republic of Korea.
Dongguk University · KRSeokyeong University · KRInsilicogen (South Korea) · KR

Funding

Ministry of Environment RE202201850
6 · The paper itself

Abstract

Heavy metals are defined as metals with relatively high density and atomic weight, and their various applications have raised serious concerns about the environmental impacts and potential human health effects. Chromium is an important heavy metal that is involved in biological metabolism, but Cr exposure can induce a severe impact on occupational workers or public health. In this study, we explore the toxic effects of Cr exposure through three exposure routes: dermal contact, inhalation, and ingestion. We propose the underlying toxicity mechanisms of Cr exposure based on transcriptomic data and various bioinformatic tools. Our study provides a comprehensive understanding of the toxicity mechanisms of different Cr exposure routes by diverse bioinformatics analyses.

Indexed as

ChromiumMetals, HeavyComputational BiologyGene Expression ProfilingHumansToxicogeneticsChromiumMetals, Heavychromiumgene expression profilinggene–gene interaction networkgo termmolecular network analysisroute of exposure

Identifiers

PMID36834821
PMCPMC9963995
OpenAlexW4319761540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.