Evidence map›Paper›PMID 36834810›Full record

ArticleInternational journal of molecular sciences2023

Inhibition of Sphingosine-1-Phosphate Receptor 2 by JTE013 Enhanced Alveolar Bone Regeneration by Promoting Angiogenesis.

William Lory, Bridgette Wellslager, Chao Sun, Özlem Yilmaz, Hong Yu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

William LoryDepartment of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Bridgette WellslagerDepartment of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Chao SunDivision of Laboratory Animal Resources, Medical University of South Carolina, Charleston, SC 29425, USA.
Özlem YilmazDepartment of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0003-3487-7217
Hong YuDepartment of Oral Health Sciences, College of Dental Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-0930-6810
Medical University of South Carolina · US

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
Turning on Persistence: Novel Molecular Determinants that Underpin P. gingivalis' Intracellular Survival In Epithelial CellsR01DE030313 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YILMAZ, OZLEM · 2020 to 2024
$2.3M
Targeting sphingosine-1-phosphate receptor 2 as a novel therapeutic strategy for periodontitisR15DE027324 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YU, HONG · 2018 to 2018
$437k
Role of sphingosine-1-phosphate receptor 2 in osteoblastogenesis and bone regeneration in periodontitisR21DE030865 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI YU, HONG · 2021 to 2022
$415k
The Role of Glutamine Metabolism for P. gingivalis-Induced Non-Canonical Autophagy in Epithelial CellsF31DE032273 · NIDCR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI WELLSLAGER, BRIDGETTE FRANCES · 2022 to 2023
$96k
NCATS NIH HHS UL1 TR001450NIDCR NIH HHS F31 DE032273NIDCR NIH HHS R01 DE030313NIDCR NIH HHS R15 DE027324NIDCR NIH HHS R21 DE030865
6 · The paper itself

Abstract

Sphingosine-1-phosphate receptor 2 (

Indexed as

Dimethyl SulfoxideVascular Endothelial Growth Factor AAnimalsBone RegenerationFluoresceinsMaleMiceMice, Inbred C57BLProto-Oncogene Proteins c-aktPyrazolesPyridinesSphingosine-1-Phosphate ReceptorsTransforming Growth Factor betaDimethyl SulfoxideFluoresceinsfluorexonJTE 013Proto-Oncogene Proteins c-aktPyrazolesPyridinessphingosine-1-phosphate receptor-2, mouseSphingosine-1-Phosphate ReceptorsTransforming Growth Factor betaVascular Endothelial Growth Factor Aangiogenesisbone regenerationGDF15JTE013PDGFS1PR2VEGF

Identifiers

PMID36834810
PMCPMC9967474
OpenAlexW4319763512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.