ReviewInternational journal of molecular sciences2023
Circadian Rhythms Disrupted by Light at Night and Mistimed Food Intake Alter Hormonal Rhythms and Metabolism.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
95 citing papers in PubMed, 3 syntheses or guidelines pooled it, 176 citations in OpenAlex.
- Long-term night shift work and cardiometabolic health in healthcare workers: a review of mechanisms and precision intervention strategies.Frontiers in public health · 2026Pooled it
- Food Intake According to Clock Gene Polymorphisms: A Systematic Review.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Pooled it
- The modulatory role of short-chain fatty acids on peripheral circadian gene expression: a systematic review.Frontiers in physiology · 2025Pooled it
- The swift study: dietary profiles of night shift workers characterised by overweight and obesity.European journal of nutrition · 2026Trial
- Trial
- Trial
- Simulated shift work schedules disrupts circadian rhythms and behavior in mice.Function (Oxford, England) · 2026Article
- Research Progress on Light Therapy to Improve Depressive Symptoms of Bipolar Depression.Actas espanolas de psiquiatria · 2026Review
- Shift Work and Psychological Distress Among Healthcare Workers: The Mediating Role of Sleep Quality and the Association with Job Dissatisfaction.Healthcare (Basel, Switzerland) · 2026Article
- Brighter nights, greater health risks: intensity-dependent disruptions by nighttime light exposure on sleep and metabolism in diurnal zebra finches.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
- The 24/7 lifestyle and male hormonal health: how sleep deprivation and ultra-processed foods impact testosterone and reproduction.Reviews in endocrine & metabolic disorders · 2026Review
- Association between light exposure patterns and multidimensional health outcomes in individuals with myalgic encephalomyelitis/chronic fatigue syndrome: findings from an observational cross-sectional cohort study.Journal of translational medicine · 2026Observational
- Light therapy in medicine: where do we stand?Annals of translational medicine · 2026Review
- The Co-Evolution of Sleep and Diet: Toward an Emerging Framework of Evolutionary Chrononutrition in Circadian-Metabolic Health.Nutrients · 2026Review
- Circadian rhythms and lung cancer biology and immunotherapy: Emerging opportunities and challenges.Chinese medical journal pulmonary and critical care medicine · 2026Review
- Exercise Timing in Sport: Molecular and Physiological Mechanisms Linking Performance, Recovery, and Biological Cost.International journal of molecular sciences · 2026Review
- Coffee consumption in relation to circadian syndrome in US population: a cross-sectional study.Nutrition journal · 2026Article
- Circadian disruption of brain temperature and heart rate in two periods after intracerebral hemorrhage surgery: a retrospective study.Scientific reports · 2026Article
- Circadian Reprogramming by Combined Time-Restricted Feeding and Exercise Improves Metabolic Homeostasis in Diabetes.Metabolites · 2026Article
- GLP-1 Receptor Agonists at the Crossroads of Circadian Biology, Sleep, and Metabolic Disease.International journal of molecular sciences · 2026Review
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Availability of artificial light and light-emitting devices have altered human temporal life, allowing 24-hour healthcare, commerce and production, and expanding social life around the clock. However, physiology and behavior that evolved in the context of 24 h solar days are frequently perturbed by exposure to artificial light at night. This is particularly salient in the context of circadian rhythms, the result of endogenous biological clocks with a rhythm of ~24 h. Circadian rhythms govern the temporal features of physiology and behavior, and are set to precisely 24 h primarily by exposure to light during the solar day, though other factors, such as the timing of meals, can also affect circadian rhythms. Circadian rhythms are significantly affected by night shift work because of exposure to nocturnal light, electronic devices, and shifts in the timing of meals. Night shift workers are at increased risk for metabolic disorder, as well as several types of cancer. Others who are exposed to artificial light at night or late mealtimes also show disrupted circadian rhythms and increased metabolic and cardiac disorders. It is imperative to understand how disrupted circadian rhythms alter metabolic function to develop strategies to mitigate their negative effects. In this review, we provide an introduction to circadian rhythms, physiological regulation of homeostasis by the suprachiasmatic nucleus (SCN), and SCN-mediated hormones that display circadian rhythms, including melatonin and glucocorticoids. Next, we discuss circadian-gated physiological processes including sleep and food intake, followed by types of disrupted circadian rhythms and how modern lighting disrupts molecular clock rhythms. Lastly, we identify how disruptions to hormones and metabolism can increase susceptibility to metabolic syndrome and risk for cardiovascular diseases, and discuss various strategies to mitigate the harmful consequences associated with disrupted circadian rhythms on human health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.