Evidence map›Paper›PMID 36834719›Full record

ArticleInternational journal of molecular sciences2023

Cholesterol-Lowering Activity of Vitisin A Is Mediated by Inhibiting Cholesterol Biosynthesis and Enhancing LDL Uptake in HepG2 Cells.

Yangbing Yuan, Yuanqin Zhu, Yawen Li, Xusheng Li, Rui Jiao, Weibin Bai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yangbing YuanDepartment of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.
Yuanqin ZhuDepartment of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.
Yawen LiDepartment of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.
Xusheng LiDepartment of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.
Rui JiaoDepartment of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.
Weibin BaiDepartment of Food Science and Engineering, Institute of Food Safety and Nutrition, Jinan University, Guangzhou 510632, China.
Jinan University · CN

Funding

Department of Science and Technology of Guangdong Province No. 2019A1515010683the National Science Foundation of China No. 21322235
6 · The paper itself

Abstract

Pyranoanthocyanins have been reported to possess better chemical stability and bioactivities than monomeric anthocyanins in some aspects. The hypocholesterolemic activity of pyranoanthocyanins is unclear. In view of this, this study was conducted to compare the cholesterol-lowering activities of Vitisin A with the anthocyanin counterpart Cyanidin-3-

Indexed as

AnthocyaninsProprotein Convertase 9BenzofuransCholesterolHep G2 CellsHumansPhenolsReceptors, LDLAnthocyaninsBenzofuransCholesterolPCSK9 protein, humanPhenolsProprotein Convertase 9Receptors, LDLvitisin Acholesterol biosynthesisHMGCRLDL uptakepyranoanthocyaninsVitisin A

Identifiers

PMID36834719
PMCPMC9961218
OpenAlexW4319600094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.