Evidence map›Paper›PMID 36834714›Full record

ArticleInternational journal of molecular sciences2023

The Genotype-Phenotype Correlation in Human 5α-Reductase Type 2 Deficiency: Classified and Analyzed from a SRD5A2 Structural Perspective.

Jieun Seo, Saeam Shin, Sang-Woon Kim, Su Jin Kim, Myeongseob Lee, Kyungchul Song, Junghwan Suh, Seung-Tae Lee, Yong Seung Lee, Hyun Wook Chae and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. A NovelJournal of clinical research in pediatric endocrinology · 2026
    Article
  4. Article
  5. Article
  6. A case of complete androgen insensitivity syndrome combined with bilateral inguinal hernia.Hernia : the journal of hernias and abdominal wall surgery · 2024
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Jieun SeoDepartment of Laboratory Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-0490-6059
Saeam ShinDepartment of Laboratory Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0003-1501-3923
Sang-Woon KimDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Su Jin KimDepartment of Pediatrics, Severance Children's Hospital, Institute of Endocrinology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Myeongseob LeeDepartment of Pediatrics, Severance Children's Hospital, Institute of Endocrinology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-7055-3100
Kyungchul SongDepartment of Pediatrics, Severance Children's Hospital, Institute of Endocrinology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-8497-5934
Junghwan SuhDepartment of Pediatrics, Severance Children's Hospital, Institute of Endocrinology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-2092-2585
Seung-Tae LeeDepartment of Laboratory Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Yong Seung LeeDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Hyun Wook ChaeDepartment of Pediatrics, Severance Children's Hospital, Institute of Endocrinology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-5016-8539
Ho-Seong KimDepartment of Pediatrics, Severance Children's Hospital, Institute of Endocrinology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0003-1135-099X
Jong Rak ChoiDepartment of Laboratory Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Sangwon HanDepartment of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Ahreum KwonDepartment of Pediatrics, Severance Children's Hospital, Institute of Endocrinology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-9692-2135
Yonsei University · KR

Funding

Hanim Precision Medicine Center of Yonsei University Health System 6-2021-0213
6 · The paper itself

Abstract

The phenotype of the 5α-reductase type 2 deficiency (5αRD2) by the

Indexed as

3-Oxo-5-alpha-Steroid 4-DehydrogenaseHypospadiasDisorder of Sex Development, 46,XYGenetic Association StudiesHumansMembrane ProteinsMutationOxidoreductasesRetrospective StudiesSteroid Metabolism, Inborn Errors3-Oxo-5-alpha-Steroid 4-DehydrogenaseMembrane ProteinsOxidoreductasesSRD5A2 protein, human5α-reductase deficiencydisorders of sex developmentexternal masculinization scoregenotype-phenotype correlationSRD5A2 gene

Identifiers

PMID36834714
PMCPMC9966410
OpenAlexW4319600431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.