Evidence map›Paper›PMID 36834623›Full record

ArticleInternational journal of molecular sciences2023

Notch1 Is Involved in Physiologic Cardiac Hypertrophy of Mice via the p38 Signaling Pathway after Voluntary Running.

Weiwei Zhang, Jiayi Liu, Zekang Wu, Guanwei Fan, Zhuo Yang, Chunhua Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Weiwei ZhangSchool of Medicine, Nankai University, Tianjin 300071, China.
Jiayi LiuSchool of Medicine, Nankai University, Tianjin 300071, China.ORCID 0000-0001-6590-1289
Zekang WuSchool of Medicine, Nankai University, Tianjin 300071, China.
Guanwei FanState Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
Zhuo YangSchool of Medicine, Nankai University, Tianjin 300071, China.
Chunhua LiuSchool of Medicine, Nankai University, Tianjin 300071, China.
Nankai University · CNTianjin University of Traditional Chinese Medicine · CN

Funding

111 Project of Nankai University BX15281, 202210055434, 202210055912the Key Technology R&D Program of the Science and Technology Commission Foundation of Tianjin 20YFZCSY00460
6 · The paper itself

Abstract

Appropriate exercise such as voluntary wheel-running can induce physiological cardiac hypertrophy. Notch1 plays an important role in cardiac hypertrophy; however, the experimental results are inconsistent. In this experiment, we aimed to explore the role of Notch1 in physiological cardiac hypertrophy. Twenty-nine adult male mice were randomly divided into a Notch1 heterozygous deficient control (Notch1

Indexed as

CardiomegalyHeartAnimalsMaleMiceMotor ActivityReceptor, Notch1Signal TransductionNotch1 protein, mouseReceptor, Notch1autophagycardiac hypertrophyNotch1p38voluntary running

Identifiers

PMID36834623
PMCPMC9966550
OpenAlexW4319442270

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.