Evidence map›Paper›PMID 36834605›Full record

ArticleInternational journal of molecular sciences2023

In Silico Examination of Single Nucleotide Missense Mutations in

Allison T Madsen, Deborah J Good

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Allison T MadsenDepartment of Human Nutrition, Foods and Exercise, Virginia Tech, Blacksburg, VA 24060, USA.
Deborah J GoodDepartment of Human Nutrition, Foods and Exercise, Virginia Tech, Blacksburg, VA 24060, USA.ORCID 0000-0003-0136-0975
Virginia Tech · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Continual advances in our understanding of the human genome have led to exponential increases in known single nucleotide variants. The characterization of each of the variants lags behind. For researchers needing to study a single gene, or multiple genes in a pathway, there must be ways to narrow down pathogenic variants from those that are silent or pose less pathogenicity. In this study, we use the

Indexed as

Basic Helix-Loop-Helix ProteinsInfertilityHumansMutation, MissenseNucleotidesObesityTranscription FactorsBasic Helix-Loop-Helix ProteinsNHLH2 protein, humanNucleotidesTranscription Factorsbasic helix-loop-helixnescient helix-loop-helix 2NSCL-2Prader–Willi syndrometertiary structural analysistranscription factor

Identifiers

PMID36834605
PMCPMC9968165
OpenAlexW4319317316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.