Evidence map›Paper›PMID 36834597›Full record

ArticleInternational journal of molecular sciences2023

Fluro-Protein C-Phycocyanin Docked Silver Nanocomposite Accelerates Cell Migration through NFĸB Signaling Pathway.

Harishkumar Madhyastha, Radha Madhyastha, Eshika Chakraborty, Kaushita Banerjee, Kamal Shah, Yuichi Nakajima, Nagendra Singh Chauhan, Sajitha Lulu Sudhakaran, Kaoru Ohe, Gothandam Kodiveri Muthukaliannan and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Harishkumar MadhyasthaDivision of Cardiovascular Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki 8891692, Japan.ORCID 0000-0002-7143-4821
Radha MadhyasthaDivision of Cardiovascular Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki 8891692, Japan.
Eshika ChakrabortySchool of Biosciences and Technology, Vellore Institute of Technology University, Vellore 632014, India.
Kaushita BanerjeeSchool of Biosciences and Technology, Vellore Institute of Technology University, Vellore 632014, India.
Kamal ShahInstitute of Pharmaceutical Research, GLA University, Mathura 281406, India.ORCID 0000-0003-2389-0563
Yuichi NakajimaDivision of Cardiovascular Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki 8891692, Japan.
Nagendra Singh ChauhanDrug Testing Laboratory, Avam Anusandhan Kendra, Raipur 490008, India.ORCID 0000-0001-6748-5004
Sajitha Lulu SudhakaranSchool of Biosciences and Technology, Vellore Institute of Technology University, Vellore 632014, India.
Kaoru OheDepartment of Applied Chemistry, Faculty of Engineering, University of Miyazaki, Miyazaki 8892192, Japan.
Gothandam Kodiveri MuthukaliannanSchool of Biosciences and Technology, Vellore Institute of Technology University, Vellore 632014, India.ORCID 0000-0003-1576-5324
Abilash Valsala GopalakrishnanSchool of Biosciences and Technology, Vellore Institute of Technology University, Vellore 632014, India.ORCID 0000-0003-0780-0492
Masugi MaruyamaDivision of Cardiovascular Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki 8891692, Japan.
Nozomi WatanabeDivision of Cardiovascular Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki 8891692, Japan.
University of Miyazaki · JPVellore Institute of Technology University · INGLA University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, there is a great demand for the development of nanomedicine aided wound tissue regeneration via silver doped nanoceuticals. Unfortunately, very little research is being carried out on antioxidants-doped silver nanometals and their interaction on the signaling axis during the bio-interface mechanism. In this study, c-phycocyanin primed silver nano hybrids (AgcPCNP) were prepared and analyzed for properties such as cytotoxicity, metal decay, nanoconjugate stability, size expansion, and antioxidant features. Fluctuations in the expression of marker genes during cell migration phenomena in in vitro wound healing scenarios were also validated. Studies revealed that physiologically relevant ionic solutions did not exhibit any adverse effects on the nanoconjugate stability. However, acidic, alkali, and ethanol solutions completely denatured the AgcPCNP conjugates. Signal transduction RT

Indexed as

NanocompositesSilverCell MovementNanoconjugatesPhosphatidylinositol 3-KinasesPhycocyaninProtein CSignal TransductionNanoconjugatesPhosphatidylinositol 3-KinasesPhycocyaninProtein CSilvercell migrationcell proliferationfibroblast cellsNFĸB pathwaysilver doped C-phycocyanin (AgcPCNP)wound healing

Identifiers

PMID36834597
PMCPMC9962756
OpenAlexW4319317448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.