Evidence map›Paper›PMID 36834554›Full record

ReviewInternational journal of molecular sciences2023

Protective Barriers Provided by the Epidermis.

Sarah de Szalay, Philip W Wertz

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07376148 (Fractional CO2 Laser-assisted Delivery of Hyaluronic Acid, Ascorbic Acid and Sodium DNA For Enhancing Facial Skin Quality in Individuals Over the Age of 30), which is not on this map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
23.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07376148 phase4recruitingnot on this mapstarted 2025, after this paper: background citation

Fractional CO2 Laser-assisted Delivery of Hyaluronic Acid, Ascorbic Acid and Sodium DNA For Enhancing Facial Skin Quality in Individuals Over the Age of 30

TypeinterventionalSponsorInstituto de Oftalmología Fundación Conde de ValencianaRan2025 to 2026Enrolled30ConditionsSkin Quality Improvement, Photo-aged Skin, Drug Delivery SystemsArmstopical hyaluronic acid, ascorbic acid, and sodium DNA following ablative fractional laser treatment
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Sweat components as a promising monitoring tool for systemic diseases.The journal of physiological sciences : JPS · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sarah de SzalaySarah de Szalay Consulting, LLC, Wesy Milford, NJ 07480, USA.
Philip W WertzDows Institute for Dental Research, College of Dentistry, University of Iowa, Iowa City, IA 52240, USA.ORCID 0000-0002-2829-5475
University of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin is the largest organ of the body and consists of an epidermis, dermis and subcutaneous adipose tissue. The skin surface area is often stated to be about 1.8 to 2 m

Indexed as

EpidermisSkinEpidermal CellsLangerhans CellsLipidsLipidsantimicrobial lipidsantimicrobial peptidesbarrier functionepidermisLangerhans cellsmelanocytes

Identifiers

PMID36834554
PMCPMC9961209
OpenAlexW4319317731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.